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鹦鹉热衣原体引起的动物源非典型性肺炎:台湾首例鹦鹉热病例报告。

Zoonotic atypical pneumonia due to Chlamydophila psittaci: first reported psittacosis case in Taiwan.

机构信息

Division of Infectious Diseases, Department of Internal Medicine, Changhua Christian Hospital, Taiwan.

出版信息

J Formos Med Assoc. 2013 Jul;112(7):430-3. doi: 10.1016/j.jfma.2012.08.017. Epub 2012 Oct 5.

DOI:10.1016/j.jfma.2012.08.017
PMID:23927984
Abstract

Human psittacosis caused by Chlamydophila psittaci is one of the most common zoonotic atypical pneumonias featuring pulmonary as well as extrapulmonary infections. Most of the cases involve avian contact history especially with psittacine birds. Herein we report a 44-year-old male patient displaying atypical pneumonia symptoms of intermittent fever, dry cough, chest pain, dyspnea, headache, hepatitis, and hyponatremia. He had two sick cockatiels, one of which had died a month previously. A microimmunofluorescence test was performed to check the serum antibody levels against Chlamydophila psittaci. The serum IgM titer showed positive titer of 1:256, 1:256, and 1:128 on Days 11, 23, and 43 after disease onset, respectively. His fever subsided soon and clinical symptoms improved after minocycline was administrated on Day 12. The psittacosis case was confirmed by history of psittacine bird contact, clinical symptoms, treatment response, and positive IgM titer. To our knowledge, this is the first report of a psittacosis case in Taiwan.

摘要

鹦鹉热衣原体引起的人感染鹦鹉热是最常见的动物源性非典型性肺炎之一,具有肺部和肺外感染的特征。大多数病例涉及禽类接触史,尤其是接触过凤头鹦鹉。在此,我们报告了一例 44 岁男性患者,表现为间歇性发热、干咳、胸痛、呼吸困难、头痛、肝炎和低钠血症等非典型肺炎症状。他有两只病虎皮鹦鹉,其中一只有一个月前死亡。进行微量免疫荧光试验以检查针对鹦鹉热衣原体的血清抗体水平。在发病后第 11、23 和 43 天,血清 IgM 滴度分别显示阳性滴度为 1:256、1:256 和 1:128。米诺环素在第 12 天给药后,患者的发热很快消退,临床症状改善。鹦鹉热病例通过鹦鹉接触史、临床症状、治疗反应和 IgM 阳性滴度得到确诊。据我们所知,这是台湾首例鹦鹉热病例报告。

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A case of chlamydia psittaci caused severe pneumonia and meningitis diagnosed by metagenome next-generation sequencing and clinical analysis: a case report and literature review.鹦鹉热衣原体引起的重症肺炎和脑膜炎 1 例:宏基因组二代测序与临床分析诊断——病例报告并文献复习
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