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[Code of codon roots, determining the intra- and intermolecular interaction of amino acids in peptide chains].

作者信息

Chipens G I, Ievinia N G, Rudzish R B

出版信息

Bioorg Khim. 1991 Nov;17(11):1582-4.

PMID:1811544
Abstract

To study the recognition processes and interaction of peptides and proteins, a model has been suggested according to which the first steps of complex formation of molecules are defined by G/C and A/U complementarity of codon roots of amino acid forming the molecules contact sites or surfaces. In contrast to amino acid--antiamino acid interaction code (L. B. Mekler, 1969), the code of codon roots involves the interaction of amino acids independently of the base structures in nucleotide triplets in positions 1 and 3. The analysis of the spectra of point mutations homologous proteins confirms the possible role of the root code.

摘要

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