Jacob R F, Collard S M
University of Texas.
Int J Prosthodont. 1991 Jul-Aug;4(4):345-52.
The use of methyl methacrylates for cranial repairs has been well established. Procedures for sterilization of these materials include soaking in benzalkonium chloride, use of ethylene oxide gas, or cobalt 60 irradiation. Although ethylene oxide sterilization is the most common method, gas sterilization and degassing of these prefabricated implants may require almost as much time as fabrication. This study evaluated impact strength and linear dimensional change following steam autoclave sterilization of heat-processed methyl methacrylate. It was compared to an autopolymerizing methyl methacrylate for impact strength. No statistical difference was found in impact strength between nonsterile heat-processed methyl methacrylate and autoclaved heat-processed methyl methacrylate; however, both were significantly stronger than the autopolymerizing material. A statistically significant linear dimensional change of 1.211% between the autoclaved and nonsterile heat-processed methyl methacrylate was found, but was not considered clinically significant.
甲基丙烯酸甲酯用于颅骨修复已得到充分认可。这些材料的灭菌程序包括浸泡在苯扎氯铵中、使用环氧乙烷气体或钴60辐照。尽管环氧乙烷灭菌是最常用的方法，但这些预制植入物的气体灭菌和除气所需时间几乎与制造时间一样长。本研究评估了热加工甲基丙烯酸甲酯经蒸汽高压灭菌后的冲击强度和线性尺寸变化。并将其与自凝甲基丙烯酸甲酯的冲击强度进行了比较。未灭菌的热加工甲基丙烯酸甲酯和经高压灭菌的热加工甲基丙烯酸甲酯之间的冲击强度没有统计学差异；然而，两者均明显强于自凝材料。经高压灭菌和未灭菌的热加工甲基丙烯酸甲酯之间存在1.211%的统计学显著线性尺寸变化，但不认为具有临床意义。
