Berbari E J, Scherlag B J, El-Sherif N, Befeler B, Aranda J M, Lazzara R
Circulation. 1976 Aug;54(2):219-24. doi: 10.1161/01.cir.54.2.219.
A methodology is described for noninvasive recording of the electrical activity generated by the His-Purkinje system of man utilizing filtering, high amplification, and signal averaging. A waveform ranging between 1 and 10mu V was observed during the P-R segment. In many individuals, there was temporal overlap between the terminal P wave and the initial portion of the His-Purkinje waveform. In ten patients with long P-R intervals there was a strong correlation (r greater than 0.95) between the H-V time measured by electrode catheter and the duration of the His-Purkinje waveform. In two patients with atrial fibrillation the resultant His-Purkinje waveform was similar in morphology and duration to those observed in the ten patients. In each group H-V time was determined noninvasively and a waveform associated with electrical activation of the major portions of the His-Purkinje system was obtained.
本文描述了一种利用滤波、高倍放大和信号平均技术对人体希氏-浦肯野系统产生的电活动进行无创记录的方法。在P-R段期间观察到幅度在1至10微伏之间的波形。在许多个体中，终末P波与希氏-浦肯野波形的起始部分存在时间重叠。在10例P-R间期延长的患者中，通过电极导管测量的H-V时间与希氏-浦肯野波形的持续时间之间存在强相关性（r大于0.95）。在2例心房颤动患者中，所得的希氏-浦肯野波形在形态和持续时间上与10例患者中观察到的相似。在每组中，均通过无创方法确定H-V时间，并获得与希氏-浦肯野系统主要部分电激活相关的波形。
