Pradhan T K, Criss W E
Enzyme. 1976;21(4):327-31. doi: 10.1159/000458875.
The major enzymatic forms of adenylate kinase have been purified to homogeneity from fetal liver and adult brain of the rat. The two enzymes differ with respect to isoelectric points, Km (ATP), Km (AMP), and Ka (citrate). Antibody to adult liver adenylate kinase does not inhibit either enzyme, while entibody to adult skeletal muscle enzyme inhibits the brain enzyme but not the fetal liver enzyme. It is therefore probable that there are three major forms of adenylate kinases in fetal and adult rat tissues.
腺苷酸激酶的主要酶形式已从大鼠的胎肝和成年大脑中纯化至同质。这两种酶在等电点、Km（ATP）、Km（AMP）和Ka（柠檬酸盐）方面存在差异。针对成年肝脏腺苷酸激酶的抗体不会抑制任何一种酶，而针对成年骨骼肌酶的抗体则会抑制大脑中的酶，但不会抑制胎肝中的酶。因此，在胎儿和成年大鼠组织中可能存在三种主要形式的腺苷酸激酶。
