Sakaguchi Y, Kato S, Kawamoto A, Uemura S, Sutani T, Kagoshima T, Ishikawa H, Okada R
First Department of Internal Medicine, Nara Medical University, Japan.
Acta Pathol Jpn. 1991 Oct;41(10):730-6. doi: 10.1111/j.1440-1827.1991.tb03344.x.
To study age-related changes in the left bundle branch (LBB), 32 autopsied hearts were examined histopathologically using serial sections according to the method of Lev. Each division of LBB was carefully studied, i.e., the anterior and posterior radiations and the proximal, middle, and distal portions of radiations. An increase of fibrosis and fatty infiltration were observed in the LBB with aging. There was a tendency for fibrosis to be more prominent in the proximal LBB at the site of transition from bundle branch cells to Purkinje cells.
