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Protein-engineered proteinase of myeloblastosis associated virus, an enzyme of high activity and HIV-1 proteinase-like specificity.

作者信息

Strop P, Horejsí M, Konvalinka J, Skrabana R, Velek J, Bláha I, Cerná V, Pichová I, Pavlícková L, Andreánsky M

机构信息

Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, Prague.

出版信息

Adv Exp Med Biol. 1991;306:515-8. doi: 10.1007/978-1-4684-6012-4_68.

DOI:10.1007/978-1-4684-6012-4_68
PMID:1812751
Abstract
摘要

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1
Protein-engineered proteinase of myeloblastosis associated virus, an enzyme of high activity and HIV-1 proteinase-like specificity.
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6
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An engineered retroviral proteinase from myeloblastosis associated virus acquires pH dependence and substrate specificity of the HIV-1 proteinase.一种源自成髓细胞瘤相关病毒的工程逆转录病毒蛋白酶获得了HIV-1蛋白酶的pH依赖性和底物特异性。
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