Eron L, Kosinski K, Hirsch M S
Gastroenterology. 1976 Sep;71(3):500-4.
Disseminated infection caused by Herpes simplex virus (HSV) type I is described in a previously healthy adult. The clinical course was characterized by progressive hepatic failure, fever, hypotension, atypical lymphocytosis, and disseminated intravascular coagulation. No skin lesions were present and the causal agent was not suspended premortem; however, HSV-I was isolated from autopsy liver, and characteristic histopathological lesions of herpes infection were observed in liver and esophagus.
一名既往健康的成年人出现了由I型单纯疱疹病毒(HSV)引起的播散性感染。临床病程的特点为进行性肝衰竭、发热、低血压、非典型淋巴细胞增多及弥散性血管内凝血。未出现皮肤损害,且生前未怀疑病原体;然而,尸检时从肝脏分离出HSV-I,并在肝脏和食管中观察到疱疹感染的特征性组织病理学病变。