Tseng P W, Newcomb G M
Department of Periodontics, Westmead Hospital Dental Clinical School, Australia.
J Clin Dent. 1991;2(4):83-6.
The adjunctive effects of subgingival chlorhexidine irrigation on gingival response following scaling and root planing were investigated. Changes in clinical parameters, and microbial composition of subgingival plaque as monitored by dark-field microscopy were assessed in 12 patients over a period of 12 weeks. Two test sites and two matched control sites with probing depth ranging from 4 mm to 7 mm were selected in each patient. Oral hygiene instruction and a single episode of scaling and root planing were carried out. In addition test sites were irrigated with one mL of 0.2% chlorhexidine solution by the operator, while control sites were either irrigated with an equal volume of physiological saline or not irrigated. There were significant improvements in the clinical parameters with little difference between test and control sites. Between the beginning and the end of the study there was a marked reduction in the proportion of spirochaetes with a concomitant increase in coccoid organisms with, again, only minor differences between the test and the control sites. It was concluded that subgingival irrigation with a single application of 0.2% chlorhexidine did not enhance gingival healing, or delay recolonization of pockets by certain micro-organisms (as monitored by dark-field microscopy), when scaling and root planing had been thoroughly carried out immediately prior to irrigation.
研究了龈下洗必泰冲洗对龈下刮治和根面平整术后牙龈反应的辅助作用。在12周的时间里，对12例患者进行了临床参数变化以及通过暗视野显微镜监测的龈下菌斑微生物组成变化的评估。在每位患者中选择两个试验部位和两个匹配的对照部位，探诊深度为4毫米至7毫米。进行了口腔卫生指导以及单次龈下刮治和根面平整。此外，由操作人员用1毫升0.2%的洗必泰溶液冲洗试验部位，而对照部位则用等体积的生理盐水冲洗或不冲洗。临床参数有显著改善，试验部位和对照部位之间差异不大。在研究开始和结束之间，螺旋体的比例显著降低，球菌类生物随之增加，试验部位和对照部位之间同样只有微小差异。得出的结论是，在冲洗前立即彻底进行龈下刮治和根面平整时，单次应用0.2%的洗必泰进行龈下冲洗并不能促进牙龈愈合，也不能延迟某些微生物对牙周袋的再定植（通过暗视野显微镜监测）。
