Moorhead J E, Conti A J, Marks R G, Cancro L P
Div. of Biostatistics, University of Florida, Gainesville.
J Clin Dent. 1991;2(4):97-102.
A supervised brushing program was incorporated into a three-year caries clinical trial whose primary objective was to compare the efficacy between two fluoride levels of a dentifrice (1,000 and 1,500 ppm F MFP). For each of the 2,415 children completing the three-year study, the total number of supervised brushing sessions completed was available. Results indicated that children who complied well with the supervised brushing program by participating in at least 70% of the sessions had a significantly lower caries increment in both fluoride levels (p less than .001) than children who did not comply as well. After adjusting for age, sex, and baseline DMFS of the children, as well as the fluoride level received, a multiple regression model showed that supervised brushing further reduced the three year caries increment (p less than .04). The more frequent use of the higher fluoride dentifrice affords the greatest prevention of decay. The conclusion from this study is that compliance with the supervised brushing program resulted in a reduced caries increment regardless of the level of fluoride in the dentifrice.
一个有监督的刷牙项目被纳入了一项为期三年的龋齿临床试验，该试验的主要目的是比较两种氟含量（1000 ppm和1500 ppm氟化物单氟磷酸钠）牙膏的功效。对于完成三年研究的2415名儿童中的每一名，都有其完成的有监督刷牙次数的总数记录。结果表明，与未很好遵守项目的儿童相比，那些通过参加至少70%的刷牙次数而很好遵守有监督刷牙项目的儿童，在两种氟含量水平下龋齿增加量都显著更低（p小于0.001）。在对儿童的年龄、性别、基线龋失补牙面数（DMFS）以及所接受的氟含量水平进行校正后，一个多元回归模型显示，有监督的刷牙进一步降低了三年的龋齿增加量（p小于0.04）。更频繁地使用高氟牙膏能提供最大程度的防龋效果。这项研究的结论是，无论牙膏中的氟含量水平如何，遵守有监督的刷牙项目都会导致龋齿增加量减少。
