Lu K H, Ruhlman C D, Chung K L, Sturzenberger O P, Lehnhoff R W
ASDC J Dent Child. 1987 Jul-Aug;54(4):241-4.
This study compared the anticaries effects of these three fluoride-containing dentifrices: 1100 ppm F as NaF (positive control); 2800 ppm F as SMFP; and 2800 ppm F as NaF. The group using the 2800 SMFP dentifrice showed no significant differences in DMFS or DMFT, compared to the positive control, at anytime during the study. This indicated that higher levels of sodium monofluorophosphate in a dentifrice offer no advantage in caries protection over the conventional level of sodium fluoride, 1100 ppm F.
含1100 ppm氟(以氟化钠形式存在)的牙膏(阳性对照);含2800 ppm氟(以单氟磷酸钠形式存在)的牙膏;以及含2800 ppm氟(以氟化钠形式存在)的牙膏。在研究期间的任何时候,使用含2800 ppm单氟磷酸钠牙膏的组与阳性对照组相比,在龋失补牙面数(DMFS)或龋失补牙数(DMFT)方面均无显著差异。这表明,牙膏中较高水平的单氟磷酸钠在预防龋齿方面并不比传统水平的1100 ppm氟化钠具有优势。