Schleyer M, Voigt K H, Pfeiffer E F
Horm Metab Res. 1976 May;8(3):175-81. doi: 10.1055/s-0028-1093655.
The preparation of two highly purified lipolytically active hog pituitary peptides, called P-LF II C and P-LF II D is described. The two peptides are free of other pituitary hormone activities. In isolated rat and porcine adipose tissue, both fractions are lipolytically much more active than every other lipolytic active pituitary peptide described to date. By fraction P-LF II D, the first pituitary peptide was isolated which has lipolytic activity in isolated rat adipose tissue than corticotropin, the lipolytically most active pituitary hormone known so far. On isolated porcine adipose tissue, fraction P-LF II D as well as P-LF II C showed without doubt higher activity than corticotropin.
本文描述了两种高度纯化的具有脂解活性的猪垂体肽，即P-LF II C和P-LF II D的制备方法。这两种肽不具有其他垂体激素活性。在分离的大鼠和猪脂肪组织中，这两个组分的脂解活性均比迄今所描述的其他任何具有脂解活性的垂体肽高得多。通过P-LF II D组分，首次分离出一种垂体肽，其在分离的大鼠脂肪组织中的脂解活性高于促肾上腺皮质激素，促肾上腺皮质激素是迄今为止已知的脂解活性最高的垂体激素。在分离的猪脂肪组织上，P-LF II D组分以及P-LF II C组分无疑显示出比促肾上腺皮质激素更高的活性。
