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[大肠腺癌中的移行黏膜。黏蛋白组织化学及扫描电子显微镜研究]

[Transitional mucosa in carcinoma of large bowel. Mucin histochemical and scanning electron microscopical study].

作者信息

Xie Q

机构信息

Xing qiao Hospital, Third Military Medical college, Chongqing.

出版信息

Zhonghua Wai Ke Za Zhi. 1991 Sep;29(9):545-7, 588-9.

PMID:1813255
Abstract

We studied the mucosa close to the carcinoma of large bowel (CLB) in 200 cases, the carcinoma tissue of CLB in 130 and the mucosa of fetus large bowel in 24 by mucin histochemistry, in addition to the mucosa near CLB studied by scanning electron microscope (SEM) in 25. The results suggested that mucin composition of transitional mucosa (TM) was similar to CLB and large bowel mucosa of the fetus. SEM showed significant changes in TM. The HID/AB Stain suggesting abnormal range of TM was within 2 cm in 68.0% (136/200) of cases of CLB, within 3 cm in 88.5% (177/200) and In SEM abnormal range within 2 cm in 88.0% (22/25). The measurement of TM can provide reference for resectable range of CLB.

摘要

我们采用黏蛋白组织化学方法,对200例大肠肿瘤旁黏膜(CLB)、130例CLB癌组织及24例胎儿大肠黏膜进行了研究,另外还用扫描电子显微镜(SEM)对25例CLB旁黏膜进行了观察。结果显示,移行黏膜(TM)的黏蛋白组成与CLB及胎儿大肠黏膜相似。SEM显示TM有显著变化。HID/AB染色显示,68.0%(136/200)的CLB病例中TM异常范围在2cm以内,88.5%(177/200)在3cm以内;而在SEM观察中,88.0%(22/25)的病例TM异常范围在2cm以内。对TM的测量可为CLB的可切除范围提供参考。

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