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从小儿腹泻病例中分离出一种可滤过性病原体,该病原体可导致犊牛腹泻。

Isolation from cases of infantile diarrhea of a filtrable agent causing diarrhea in calves.

作者信息

LIGHT J S, HODES H L

出版信息

J Exp Med. 1949 Aug 1;90(2):113-35. doi: 10.1084/jem.90.2.113.

DOI:10.1084/jem.90.2.113
PMID:18136193
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2135903/
Abstract

From instances of diarrhea of the newborn in four separate hospital outbreaks a filtrable agent was isolated which regularly produced diarrhea in calves. This agent appeared to have the characteristics of a filtrable virus. The four strains of virus isolated in the outbreaks studied appeared to be identical or very closely related. The virus was not found present in the stools of any of eight normal newborn infants or five normal calves. Evidence is presented that the virus may be one of the causes of epidemic diarrhea of the newborn.

摘要

在四家不同医院爆发的新生儿腹泻病例中,分离出一种可滤过性病原体,该病原体可使小牛定期出现腹泻。这种病原体似乎具有可滤过性病毒的特征。在所研究的疫情中分离出的四株病毒似乎相同或密切相关。在八名正常新生儿和五头正常小牛的粪便中均未发现该病毒。有证据表明,该病毒可能是新生儿流行性腹泻的病因之一。

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J Exp Med. 1949 Aug 1;90(2):113-35. doi: 10.1084/jem.90.2.113.
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本文引用的文献

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TRANSMISSION OF EPIDEMIC GASTROENTERITIS TO HUMAN VOLUNTEERS BY ORAL ADMINISTRATION OF FECAL FILTRATES.经口摄入粪便滤液将肠道传染病传染给人类志愿者。
J Exp Med. 1947 Oct 31;86(5):409-22. doi: 10.1084/jem.86.5.409.
2
A FILTERABLE VIRUS CAUSING ENTERITIS AND PNEUMONIA IN CALVES.能滤过的病毒引起犊牛肠炎和肺炎。
J Exp Med. 1943 Dec 1;78(6):435-46. doi: 10.1084/jem.78.6.435.
3
A VIRUS DISEASE OF CATS, PRINCIPALLY CHARACTERIZED BY ALEUCOCYTOSIS, ENTERIC LESIONS AND THE PRESENCE OF INTRANUCLEAR INCLUSION BODIES.猫的一种病毒性疾病,主要特征为白细胞减少症、肠损伤和核内包涵体的存在。
J Exp Med. 1939 Feb 28;69(3):327-52. doi: 10.1084/jem.69.3.327.
4
Epidemic diarrheal disease of suckling mice; cytoplasmic inclusion bodies in intestinal epithelium in relation to the disease.乳鼠流行性腹泻病;肠道上皮细胞中的胞质包涵体与该疾病的关系。
J Exp Med. 1948 Sep 1;88(3):317-24. doi: 10.1084/jem.88.3.317.
5
Epidemic diarrheal disease of suckling mice; the effect of strain, litter, and season upon the incidence of the disease.乳鼠流行性腹泻病;毒株、窝别和季节对该病发病率的影响。
J Exp Med. 1948 Sep 1;88(3):309-16. doi: 10.1084/jem.88.3.309.
6
Studies on Epidemic Diarrhea of the New-born: Isolation of a Filtrable Agent Causing Diarrhea in Calves.新生儿流行性腹泻研究:一种可滤过性致病因子的分离,该因子可引发犊牛腹泻
Am J Public Health Nations Health. 1943 Dec;33(12):1451-4. doi: 10.2105/ajph.33.12.1451.