Scott T A, Augsburger J J, Brady L W, Hernandez C, Woodleigh R
Oncology Unit, Wills Eye Hospital, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Retina. 1991;11(4):389-93. doi: 10.1097/00006982-199111040-00004.
The authors describe five eyes in four patients with diffuse choroidal hemangiomas associated with progressive serous nonrhegmatogenous retinal detachment that were treated with low dose external beam ocular irradiation (1,250 to 2,000 cGy in multiple fractions). The subretinal fluid reabsorbed completely within 3 to 12 months of treatment in every case and there has been no reaccumulation in any case to date (median follow-up 14 months). Two of the patients have developed a focal posterior subcapsular radiation cataract in the treated eye (at 19 months and 66 months, respectively, after irradiation), but none of the patients has thus far developed radiation retinopathy. The authors discuss the potential benefits and risks of this form of treatment for choroidal hemangiomas with bullous retinal detachment.
作者描述了4例患有弥漫性脉络膜血管瘤并伴有进行性浆液性非孔源性视网膜脱离的患者的5只眼睛,这些眼睛接受了低剂量眼外照射(分多次给予1250至2000 cGy)治疗。在每例患者中,视网膜下液在治疗后的3至12个月内完全吸收,迄今为止,没有任何病例出现再次积聚(中位随访时间为14个月)。2例患者在接受治疗的眼睛中出现了局限性后囊下放射性白内障(分别在照射后的19个月和66个月),但迄今为止,没有患者出现放射性视网膜病变。作者讨论了这种治疗方法对伴有大泡性视网膜脱离的脉络膜血管瘤的潜在益处和风险。