Plant C G, Tobias R S, Rippin J W, Brooks J W, Browne R M
Department of Restorative Dentistry, University of Birmingham Dental School.
Dent Mater. 1991 Oct;7(4):217-24. doi: 10.1016/S0109-5641(05)80018-1.
This investigation was designed to study the pulpal responses to glass-ionomer base materials that differ in particle size distribution. The study was carried out according to the BSI (1980) recommendations for testing restorative materials in vivo. The base materials caused more pulpal inflammation than the control material, Kalzinol, although by an indirect mechanism. A significant association was demonstrated in the statistical model between bacterial presence within the experimental cavity and pulpal inflammation. The type of restorative material has no direct association with the degree of inflammation, although the model suggests that it exerts an indirect influence via its antibacterial properties, and hence its influence on microbial microleakage. The base material, with a heterogeneous particle distribution, was associated with greater bacterial microleakage. Particle size distribution, therefore, has some effect upon bacterial microleakage, but, because of its complex effect upon several physical properties of materials, further studies are indicated.
本研究旨在探讨不同粒度分布的玻璃离子基牙材料对牙髓的反应。该研究按照英国标准学会（1980年）体内测试修复材料的建议进行。尽管是通过间接机制，但基牙材料比对照材料Kalzinol引起了更多的牙髓炎症。在实验腔体内细菌存在与牙髓炎症之间的统计模型中显示出显著关联。修复材料的类型与炎症程度没有直接关联，尽管该模型表明它通过其抗菌性能发挥间接影响，从而对微生物微渗漏产生影响。具有不均匀颗粒分布的基牙材料与更大的细菌微渗漏相关。因此，粒度分布对细菌微渗漏有一定影响，但由于其对材料多种物理性能的复杂影响，还需要进一步研究。
