Tarim B, Hafez A A, Cox C F
Department of Conservative Dentistry, Faculty of Dentistry, Istanbul University, Turkey.
Quintessence Int. 1998 Aug;29(8):535-42.
This study evaluated the biocompatibility of a resin-modified glass-ionomer material on monkey pulps.
Standardized Class V cavities were prepared in 112 teeth distributed in six healthy adult monkeys. The resin-modified glass-ionomer cement was placed in 24 nonexposed and 36 exposed pulps according to manufacturer's instructions. ZOE was used as a control in nonexposed pulps, while calcium hydroxide was used as a control for exposed pulps. Tissues were collected at 6 to 7, 21 to 27, and 90 to 97 days. After demineralization, the teeth were serially sectioned, stained, and observed by light microscopy.
Except for one resin-modified glass-ionomer pulp at 6 days, there were no differences between the responses of nonexposed pulps to resin-modified glass-ionomer specimens and ZOE controls. In exposed pulps, eight of 36 resin-modified glass-ionomer pulps showed various grades of inflammatory response, all associated with stained bacteria. Pulpal healing was similar in both resin-modified glass-ionomer and calcium hydroxide direct-capped exposures. Twenty-two of 26 exposed pulps restored with the resin-modified glass-ionomer cement showed dentin bridge formation at 21 and 97 days.
The resin-modified glass-ionomer material exhibited acceptable biologic compatibility in exposed and nonexposed cavities.
本研究评估了一种树脂改性玻璃离子材料对猴牙髓的生物相容性。
在6只健康成年猴的112颗牙齿上制备标准化的V类洞。按照制造商的说明，将树脂改性玻璃离子水门汀放置于24颗未暴露牙髓和36颗暴露牙髓中。在未暴露牙髓中，使用氧化锌丁香酚水门汀作为对照，而在暴露牙髓中，使用氢氧化钙作为对照。在6至7天、21至27天和90至97天时收集组织。脱矿后，将牙齿进行连续切片、染色，并通过光学显微镜观察。
除了1颗在6天时的树脂改性玻璃离子牙髓外，未暴露牙髓对树脂改性玻璃离子标本和氧化锌丁香酚水门汀对照的反应之间没有差异。在暴露牙髓中，36颗树脂改性玻璃离子牙髓中有8颗显示出不同程度的炎症反应，均与染色细菌有关。树脂改性玻璃离子和氢氧化钙直接盖髓后的牙髓愈合情况相似。用树脂改性玻璃离子水门汀修复的26颗暴露牙髓中有22颗在21天和97天时显示有牙本质桥形成。
树脂改性玻璃离子材料在暴露和未暴露的洞中均表现出可接受的生物相容性。
Zotero 插件