Hussain S M, Meradji M, Robben S G, Hop W C
Department of Pediatric Radiology, Sophia Children's Hospital, Erasmus University, Rotterdam, The Netherlands.
Pediatr Radiol. 1991;21(8):556-9. doi: 10.1007/BF02012596.
Abdominal plain films of 133 neonates, with 82 cases of meconium plug syndrome (MPS), 27 cases of meconium ileus (MI) and 24 cases of neonatal Hirschsprung's disease (HD), were reviewed to assess the value of such radiographs for diagnosis. The radiographs were examined according to a list of 11 parameters. By using multivariate discriminant analysis, it appeared that 4 parameters i.e. dilatation of bowel loops, varying loop calibre, fluid levels and colonic gas were most important in discriminating among the three disorders. For each parameter the weight (in points) was derived. To classify patients, three group-scores had to be calculated: the group-score with the largest value indicated the most likely disorder. So in 99%, 88% and 63% of MPS, HD and MI, respectively, an accurate diagnosis could be predicted. The overall diagnostic accuracy was 89%. Such a diagnosis can be a sound basis for further investigation.
回顾了133例新生儿的腹部平片，其中82例为胎粪栓塞综合征（MPS），27例为胎粪性肠梗阻（MI），24例为新生儿先天性巨结肠（HD），以评估此类X线片的诊断价值。根据11项参数清单对X线片进行检查。通过多变量判别分析，发现4项参数，即肠袢扩张、肠袢管径变化、液平面和结肠气体，在区分这三种疾病中最为重要。为每个参数得出权重（以分数计）。为对患者进行分类，必须计算三个组分数：值最大的组分数表明最可能的疾病。因此，分别在99%、88%和63%的MPS、HD和MI病例中，可以预测出准确的诊断。总体诊断准确率为89%。这样的诊断可为进一步检查提供可靠依据。
