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[体外冲击波碎石术在胆结石综合治疗中的改进]

[Improvement of extracorporeal shockwave cholelithotripsy in the comprehensive treatment of cholelithiasis].

作者信息

Bagaudinov K G, Saidov S S, Garilevich B A, Zubkov A D, Abdulaev R A, Ovakimian G S

出版信息

Klin Med (Mosk). 2007;85(10):56-9.

Abstract

The method of shockwave distant lithotripsy (DL) has been used since 1985. However, many facets of this problem have not been solved yet, because large fragments of the stone remain after its destruction, and focused shock waves (FSW) damage the gallbladder (GB). The aim of this study was to determine possibilities of effective distant destruction of gall stones, to reveal negative consequences of the effects of FSW on the gallbladder (GB) and the surrounding tissues, as well as development and perfection of DL technique. The established parameters of FSW were used to develop the new Lithotriptor Compact. By now, 53 patients with cholelithiasis aged 18 to 55 have been treated by DC. The procedure was performed without general anesthesia. A thousand to 3500 shockwave impulses were applied to each stone. All patients had received litholytic therapy and treatment directed towards metabolic normalization, the functional state of the GB, and prevention of recurrent stone formation, prior to DL. In total, 116 DL sessions (2.2 sessions per a patient) were performed. A positive effect as a result of the complex treatment of cholelithiasis using DL method was achieved in 47 (88.7%) of the patients. There were no complications. In 3 patients (5.7%) recurrence of gallstones was found two years after DL sessions. Correctly selected parameters of FSW and DL technology allow for effective destruction of GB stones, while conservative therapy favors their passage through the biliary tract and fast litholysis of remaining stone fragments.

摘要

自1985年起便开始使用冲击波体外碎石术(DL)。然而,该问题的许多方面尚未得到解决,因为结石在被击碎后仍会残留大的碎片,而且聚焦冲击波(FSW)会对胆囊(GB)造成损伤。本研究的目的是确定有效远距离破坏胆结石的可能性,揭示FSW对胆囊(GB)及周围组织影响的负面后果,以及DL技术的发展与完善。利用已确定的FSW参数研发了新型Compact碎石机。截至目前,已有53例年龄在18至55岁的胆结石患者接受了DC治疗。该 procedure在未进行全身麻醉的情况下实施。对每颗结石施加1000至3500次冲击波脉冲。所有患者在接受DL治疗前均已接受溶石治疗以及针对代谢正常化、GB功能状态和预防结石复发的治疗。总共进行了116次DL治疗(每位患者2.2次)。采用DL方法综合治疗胆结石,47例(88.7%)患者取得了积极效果。未出现并发症。3例患者(5.7%)在DL治疗两年后出现胆结石复发。正确选择的FSW参数和DL技术能够有效破坏GB结石,而保守治疗则有利于结石通过胆道排出以及剩余结石碎片的快速溶解。

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