Moayeri Heshmat, Rabbani Ali, Keihanidoust Zarrin-Tag, Bidad Katayoon, Anari Shahab
Department of Pediatric Endocrinology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Arch Iran Med. 2008 Jan;11(1):10-5.
Metabolic syndrome not only is a serious problem for adults, but is also afflicting an increasing number of children and adolescents. This syndrome is a risk factor for type 2 diabetes mellitus and cardiovascular diseases. The aim of this study was to estimate the prevalence of metabolic syndrome in a sample of Iranian adolescents.
A total of 554 overweight adolescents (aged 11 - 17 years) participated in a community-based cross sectional survey. Anthropometric examinations including height, weight, body mass index, and blood pressure were assessed. A fasting blood sample was taken for measurement of glucose and lipid profile. Metabolic syndrome was determined by the definition released by the National Cholesterol Education Program Adult Treatment Panel III, which was modified for age.
The overall prevalence of metabolic syndrome was 26.6%. There was no gender difference in the distribution of metabolic syndrome. When stratified by body mass index, 22.5% were overweight (BMI> or =95th percentile) besides having the criteria for metabolic syndrome, while the remaining 4.1% of the adolescents were at risk for overweight (BMI between 85th and 95th percentile) together with metabolic syndrome. Hypertriglyceridemia was the most common and high-density lipoprotein was the least common constituent of metabolic syndrome.
This study suggests a high prevalence of metabolic syndrome among overweight Iranian adolescents. This poses a serious threat to the current and future health of Iranian youth.
代谢综合征不仅是成年人面临的严重问题，而且正困扰着越来越多的儿童和青少年。该综合征是2型糖尿病和心血管疾病的危险因素。本研究的目的是估计伊朗青少年样本中代谢综合征的患病率。
共有554名超重青少年（年龄在11至17岁之间）参与了一项基于社区的横断面调查。评估了包括身高、体重、体重指数和血压在内的人体测量指标。采集空腹血样以测量血糖和血脂谱。代谢综合征根据美国国家胆固醇教育计划成人治疗小组第三次报告发布的定义确定，并针对年龄进行了调整。
代谢综合征的总体患病率为26.6%。代谢综合征的分布不存在性别差异。按体重指数分层时，22.5%的人除了符合代谢综合征标准外还超重（体重指数大于或等于第95百分位数），而其余4.1%的青少年处于超重风险（体重指数在第85至95百分位数之间）且患有代谢综合征。高甘油三酯血症是代谢综合征最常见的组成部分，而高密度脂蛋白是最不常见的组成部分。
本研究表明超重的伊朗青少年中代谢综合征的患病率很高。这对伊朗青年当前和未来的健康构成了严重威胁。
