Anaya-Saavedra Gabriela, Ramírez-Amador Velia, Irigoyen-Camacho María Esther, Zimbrón-Romero Araceli, Zepeda-Zepeda Marco Antonio
Universidad Autónoma Metropolitana-Xochimilco, Calzada del Hueso 1100, Col. Villa Quietud, México D.F., México.
J Oral Pathol Med. 2008 Jan;37(1):11-7. doi: 10.1111/j.1600-0714.2007.00562.x.
In Mexico, information on oral and pharyngeal cancer (OPC) is scarce. The purpose of this study was to explore the trends in OPC mortality rates in Mexico from 1979 through 2003 and to describe the distribution of OPC deaths for selected socio-demographic variables for the period of 2001-2003.
Annual crude and age-adjusted mortality rates were obtained by gender and site of lesion, using the 2003 WHO World standard million population. The Poisson regression model was used to detect a trend in the mortality rates, testing the hypothesis beta(1) = 0. Also, the annual percentage change (APC) was computed over the age-adjusted rates.
The total number of OPC deaths during the period 1979-2003 was 15,576. The age-adjusted mortality rate was 1.13/100,000 in 1979 and 1.08/100,000 in 2003. Oral cancer was more frequently found than salivary gland and pharyngeal cancer (41.5% vs. 13.4% and 17.1%). The tongue (19%) was the most frequent oral affected site. The Poisson regression analysis indicated a stationary trend in cancer mortality rate; also, the APC regression model showed no increase or decrease in OPC from 1979 to 2003.
Oral and pharyngeal cancer mortality rates in Mexico were low compared to most countries, and remained stable in the past two decades.
在墨西哥，关于口腔和咽癌（OPC）的信息匮乏。本研究的目的是探究1979年至2003年墨西哥OPC死亡率的趋势，并描述2001 - 2003年期间选定社会人口学变量的OPC死亡分布情况。
使用2003年世界卫生组织世界标准百万人口，按性别和病变部位获取年度粗死亡率和年龄调整死亡率。采用泊松回归模型检测死亡率趋势，检验β(1)=0的假设。此外，计算年龄调整率的年度百分比变化（APC）。
1979年至2003年期间OPC死亡总数为15576例。1979年年龄调整死亡率为1.13/10万，2003年为1.08/10万。口腔癌比唾液腺癌和咽癌更常见（41.5%对13.4%和17.1%）。舌部（19%）是最常受影响的口腔部位。泊松回归分析表明癌症死亡率呈平稳趋势；此外，APC回归模型显示1979年至2003年OPC无增加或减少。
与大多数国家相比，墨西哥口腔和咽癌死亡率较低，且在过去二十年中保持稳定。
