Rohrer James E, Anderson Gregory J, Furst Joseph W
Department of Family Medicine, Mayo Clinic, Rochester, Minnesota USA.
BMC Health Serv Res. 2007 Dec 21;7:212. doi: 10.1186/1472-6963-7-212.
Prevention of pre-hypertension is an important goal for primary care patients. Obesity is a risk factor for hypertension, but has not been addressed for pre-hypertension in primary care populations. The objective of this study was to assess the degree to which obesity independently is associated with risk for pre-hypertension in family medicine patients.
This study was a retrospective analysis of information abstracted from medical records of 707 adult patients. Multivariable logistic regression was used to test the relationship between body mass index (BMI) and pre-hypertension, after adjustment for comorbidity and demographic characteristics. Pre-hypertension was defined as systolic pressure between 120 and 139 mm Hg or diastolic pressure between 80 and 89 mm Hg.
In our sample, 42.9% of patients were pre-hypertensive. Logistic regression analysis revealed that, in comparison to patients with normal body mass, patients with BMI > 35 had higher adjusted odds of being pre-hypertensive (OR = 4.5, CI 2.55-8.11, p < .01). BMI between 30 and 35 also was significant (OR = 2.7, CI 1.61-4.63, p < 0.01) as was overweight (OR = 1.8, CI 1.14-2.92, p = 0.01).
In our sample of family medicine patients, elevated BMI is a risk factor for pre-hypertension, especially BMI > 35. This relationship appears to be independent of age, gender, marital status and comorbidity. Weight loss intervention for obese patients, including patient education or referral to weight loss programs, might be effective for prevention of pre-hypertension and thus should be considered as a potential quality indicator.
预防高血压前期是初级保健患者的重要目标。肥胖是高血压的一个危险因素,但在初级保健人群中,高血压前期尚未得到关注。本研究的目的是评估肥胖在多大程度上独立与家庭医学患者的高血压前期风险相关。
本研究是对707例成年患者病历信息的回顾性分析。在对合并症和人口统计学特征进行调整后,使用多变量逻辑回归来检验体重指数(BMI)与高血压前期之间的关系。高血压前期定义为收缩压在120至139毫米汞柱之间或舒张压在80至89毫米汞柱之间。
在我们的样本中,42.9%的患者患有高血压前期。逻辑回归分析显示,与体重正常的患者相比,BMI>35的患者患高血压前期的校正比值更高(OR=4.5,CI 2.55-8.11,p<.01)。BMI在30至35之间也具有显著性(OR=2.7,CI 1.61-4.63,p<0.01),超重也是如此(OR=1.8,CI 1.14-2.92,p=0.01)。
在我们的家庭医学患者样本中,BMI升高是高血压前期的一个危险因素,尤其是BMI>35。这种关系似乎独立于年龄、性别、婚姻状况和合并症。对肥胖患者进行体重减轻干预,包括患者教育或转介至体重减轻计划,可能对预防高血压前期有效,因此应被视为一个潜在的质量指标。