Wudel James H, Chaudhuri Pradipta, Hiller Jeffery J
Nebraska Heart Hospital, Lincoln, Nebraska 68506, USA.
Ann Thorac Surg. 2008 Jan;85(1):34-8. doi: 10.1016/j.athoracsur.2007.08.014.
New ablation technologies have spurred development of less invasive operations for atrial fibrillation. The long-term efficacy of these procedures is unknown.
This was a retrospective study of 22 patients aged 63 +/- 9 years with symptomatic, intermittent atrial fibrillation who underwent video-assisted, thoracoscopic pulmonary vein isolation and left atrial appendage exclusion from April 2004 through July 2005. The procedure consisted of bilateral 10-mm ports and 5-cm non-rib-spreading working ports. The left atrial appendage was excised with a surgical stapler. All patients were followed for at least 1 year, and all underwent Holter monitoring at study end point.
The procedure was performed safely in all patients. One patient did not undergo left atrial appendage excision because of preexisting adhesions. No stroke, reoperation for bleeding, or patient mortality occurred. Average hospital stay was 3.2 +/- 2.0 days (range, 2 to 10 days). No patient required repeat atrial fibrillation ablation. One patient underwent right atrial flutter ablation 7 months postoperatively. Average follow-up time was 18.1 +/- 4.1 months (range, 12 to 27 months). At the end of follow-up, 20 patients (91%) were free of symptoms without antiarrhythmic therapy. Holter monitoring in these patients (performed more than 6 months after cessation of antiarrhythmic drugs) showed sinus rhythm and no atrial fibrillation. Twenty patients (91%) were no longer taking warfarin at the end of the study period.
Bilateral, video-assisted, thoracoscopic pulmonary vein isolation with left atrial appendage exclusion has favorable single-procedure efficacy after extended follow-up for selected patients with atrial fibrillation.
新的消融技术推动了房颤微创治疗的发展。这些手术的长期疗效尚不清楚。
这是一项回顾性研究,对22例年龄为63±9岁、有症状的间歇性房颤患者进行了研究,这些患者在2004年4月至2005年7月期间接受了电视辅助胸腔镜肺静脉隔离和左心耳切除术。手术包括双侧10毫米端口和5厘米非肋骨撑开工作端口。用手术吻合器切除左心耳。所有患者至少随访1年,并在研究终点进行动态心电图监测。
所有患者手术均安全进行。1例患者因既往粘连未进行左心耳切除。未发生中风、因出血再次手术或患者死亡。平均住院时间为3.2±2.0天(范围2至10天)。无患者需要重复房颤消融。1例患者术后7个月进行了右房扑动消融。平均随访时间为18.1±4.1个月(范围12至27个月)。随访结束时,20例患者(91%)在未接受抗心律失常治疗的情况下无症状。这些患者(在停用抗心律失常药物6个月后进行)的动态心电图监测显示为窦性心律,无房颤。在研究期末,20例患者(91%)不再服用华法林。
对于选定的房颤患者,双侧电视辅助胸腔镜肺静脉隔离加左心耳切除在长期随访后具有良好的单次手术疗效。