[Synthesis of heterocyclic immunomodulators. 1. Alkyl derivatives of 1,2,4-dithiazolidin-3,5-diyliden-bis(o-benzoquinone-meth ide): synthesis and testing of immunomodulating action].

Reactions of 1,2,4-dithiazolidine-3,5-diylidene-bis(o-benzoquinone-met hid) 3 with alkyl and substituted benzyl or phenacyl halides yield 1,2,4-dithiazol-3-ylidene-quinone-methides 4a-4i. Mass spectral fragmentations of 4a, 4c, and 4f are discussed. Tests for immunomodulating properties of 4a-c, 4e, and 4g are described. Some of these compounds show immuno-stimulatory activity.