Zuskin E, Kanceljak B, Mustajbegović J, Kern J, Tonković-Lojović M
Skola narodnog zdravlja Andrija Stampar Medicinskog fakulteta Sveucilista u Zagrebu.
Arh Hig Rada Toksikol. 1991 Dec;42(4):349-57.
Immunological testing was carried out in 24 cotton workers and in 30 control workers. Skin prick test was performed with allergens prepared from cotton dust and cotton seed. Skin tests were positive in 33.3% and IgE level was increased in 62.5% of the cotton workers. Only two 3.3% had positive skin tests and none had increased IgE serum level. Ventilatory capacity in cotton workers with positive skin tests and those with negative skin tests was comparable. The same was true of the workers with increased and normal IgE levels. The effect of cotton dust extract on isolated tracheal smooth muscle of a guinea pig was an indication of a direct irritative action causing airway obstruction.
对24名棉纺织工人和30名对照工人进行了免疫测试。用从棉尘和棉籽制备的变应原进行皮肤点刺试验。33.3%的棉纺织工人皮肤试验呈阳性，62.5%的棉纺织工人免疫球蛋白E（IgE）水平升高。对照工人中只有2人（3.3%）皮肤试验呈阳性，且无人血清IgE水平升高。皮肤试验阳性的棉纺织工人和皮肤试验阴性的棉纺织工人的通气能力相当。IgE水平升高的工人和IgE水平正常的工人也是如此。棉尘提取物对豚鼠离体气管平滑肌的作用表明其具有直接刺激作用，可导致气道阻塞。
