D'Alonzo Richard C, White William D, Schultz John R, Jaklitsch Paul M, Habib Ashraf S
Department of Anesthesiology, Duke University Medical Center, Durham, NC.
Reg Anesth Pain Med. 2008 Jan-Feb;33(1):24-9. doi: 10.1016/j.rapm.2007.06.399.
In a pilot study, we previously demonstrated a higher average skin to lumbar epidural space distance (STLESD) in our obstetric population compared with the published literature. Furthermore, we demonstrated differences in STLESD based on ethnicity. The aim of this study was to perform a comprehensive analysis of the STLESD in our patient population by expanding the number of patients and ethnic groups included.
Data from 3,305 patients were obtained from our electronic database from September 2003 through November 2005. Self-declared ethnicity included 1,177 Caucasians (36%), 1,162 African Americans (35%), 760 Hispanics (23%), 135 Asians (4%), and 71 Indian/Pakistani/Bangladeshi/Sri Lankans (2%). The influences of body mass index (BMI), ethnicity, and their interaction on the STLESD were tested with a multiple linear regression model.
The mean +/- SD STLESD differed among the ethnic groups ranging from 4.8 +/- 0.9 cm in Asian patients to 6.3 +/- 1.6 cm in African American parturients. When all ethnic groups were compared, BMI had a significant influence on STLESD (P < .0001), but so did ethnicity (P = .0004). The Hispanic group demonstrated STLESDs that were significantly lower than the African American and Caucasian groups at high BMI (P < .0001). In a subanalysis performed without the Hispanic group, the influence of BMI on STLESD was found to be similar for each group. In this subanalysis, the African American group had STLESDs that were deeper compared with the other 3 ethnic groups (P < .0001), regardless of BMI.
In this study we found that the STLESD was deeper than what was previously reported in the literature. Furthermore, ethnicity, in addition to BMI, influenced the STLESD.
在一项初步研究中,我们先前发现,与已发表文献相比,我们产科人群的平均皮肤至腰段硬膜外腔距离(STLESD)更高。此外,我们还证明了STLESD因种族而异。本研究的目的是通过扩大纳入的患者数量和种族群体,对我们患者群体的STLESD进行全面分析。
从2003年9月至2005年11月我们的电子数据库中获取了3305例患者的数据。自我申报的种族包括1177名白种人(36%)、1162名非裔美国人(35%)、760名西班牙裔(23%)、135名亚洲人(4%)以及71名印度/巴基斯坦/孟加拉国/斯里兰卡人(2%)。使用多元线性回归模型测试体重指数(BMI)、种族及其相互作用对STLESD的影响。
不同种族的平均±标准差STLESD有所不同,亚洲患者为4.8±0.9厘米,非裔美国产妇为6.3±1.6厘米。当对所有种族进行比较时,BMI对STLESD有显著影响(P<.0001),种族也有显著影响(P =.0004)。在高BMI时,西班牙裔群体的STLESD显著低于非裔美国人和白种人群体(P<.0001)。在一项不包括西班牙裔群体的亚分析中,发现每个群体中BMI对STLESD的影响相似。在该亚分析中,无论BMI如何,非裔美国人群体的STLESD都比其他3个种族群体更深(P<.0001)。
在本研究中,我们发现STLESD比先前文献报道的更深。此外,除BMI外,种族也影响STLESD。