Carroll Joan F, Chiapa Ana L, Rodriquez Mayra, Phelps David R, Cardarelli Kathryn M, Vishwanatha Jamboor K, Bae Sejong, Cardarelli Roberto
Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, TX, USA.
Obesity (Silver Spring). 2008 Mar;16(3):600-7. doi: 10.1038/oby.2007.92. Epub 2008 Jan 17.
BMI and waist circumference are used to define risk from excess body fat. Limited data in women suggest that there may be racial/ethnic differences in visceral adipose tissue (VAT) at a given BMI or waist circumference. This study tested the hypothesis that racial/ethnic differences exist in both men and women in the relationship of anthropometric measures of body composition and computed tomography (CT)-determined VAT or subcutaneous adipose tissue (SAT).
Subjects included 66 African American, 72 Hispanic, and 47 white men and women, aged > or =45. Waist circumference and BMI were measured using standard methods. Total abdominal and L4L5 VAT and SAT were measured using CT.
Among both men and women, groups did not differ in waist circumference or BMI. White men had greater L4L5 VAT than African-American men, and both white and Hispanic men had greater total VAT than African-American men. Among women, Hispanics and whites had greater L4L5 VAT than African Americans, and Hispanics had greater total VAT than African Americans. The slope of the linear relationship between BMI or waist circumference and VAT was lower in African Americans than in Hispanics and/or whites.
Middle-aged and older African-American men and women had lower VAT despite similar BMI and waist circumference measurements. Altered relationships between anthropometric measures and VAT may have implications for defining metabolic risk in different populations. Different waist circumference or BMI cutoff points may be necessary to adequately reflect risk in different racial/ethnic groups.
体重指数（BMI）和腰围用于界定因体脂过多带来的风险。针对女性的有限数据表明，在给定的BMI或腰围水平下，内脏脂肪组织（VAT）可能存在种族/民族差异。本研究检验了这样一个假设，即无论男性还是女性，身体成分的人体测量指标与计算机断层扫描（CT）测定的VAT或皮下脂肪组织（SAT）之间的关系存在种族/民族差异。
研究对象包括66名非裔美国人、72名西班牙裔和47名白人男性及女性，年龄≥45岁。采用标准方法测量腰围和BMI。使用CT测量腹部总VAT、L4L5水平的VAT以及SAT。
在男性和女性中，各群体的腰围或BMI并无差异。白人男性L4L5水平的VAT高于非裔美国男性，白人男性和西班牙裔男性的腹部总VAT均高于非裔美国男性。在女性中，西班牙裔和白人L4L5水平的VAT高于非裔美国人，西班牙裔女性的腹部总VAT高于非裔美国女性。非裔美国人中，BMI或腰围与VAT之间线性关系的斜率低于西班牙裔和/或白人。
尽管中年及老年非裔美国男性和女性的BMI和腰围测量值相似，但他们的VAT较低。人体测量指标与VAT之间关系的改变可能对界定不同人群的代谢风险具有影响。可能需要不同的腰围或BMI切点来充分反映不同种族/民族群体的风险。
