Dimick Justin B, Welch H Gilbert
VA Outcomes Group, Department of Veterans Affairs Medical Center, White River Junction, VT 05009, USA.
J Am Coll Surg. 2008 Jan;206(1):13-6. doi: 10.1016/j.jamcollsurg.2007.07.032. Epub 2007 Oct 18.
Patients considering where to have surgery may reasonably believe that their chances of survival are highest at hospitals whose reported operative mortality is zero. We sought to determine if hospitals with zero mortality over 3 years also have lower than average mortality in the subsequent year.
We obtained national Medicare data on five operations with high operative mortality (> 4.0%): coronary artery bypass grafting, abdominal aortic aneurysm repair, and resections for colon, lung, and pancreatic cancer. For each procedure, we defined zero mortality hospitals as those with no inpatient or 30-day deaths during the 3-year period 1997 to 1999. To determine whether these hospitals actually have lower mortality than other hospitals, we compared their mortality during the next year (2000) with the mortality at all other hospitals.
For four procedures, operative mortality in zero mortality hospitals in the subsequent year was no different than that in other hospitals: abdominal aortic aneurysm repair (6.3% zero mortality hospitals versus 5.8% other hospitals; (adjusted relative risk [RR]=1.09; 95% CI 0.92 to 1.29); lobectomy for lung cancer (5.1% versus 5.3%; RR=0.96; 95% CI 0.80 to 1.15); colon cancer resection (6.0% versus 6.6%; RR=0.91; 95% CI 0.80 to 1.03); and coronary artery bypass surgery (4.0% versus 5.0%; RR=0.81; 95% CI 0.61 to 1.04). In the case of pancreatic cancer resection, zero mortality hospitals had substantially higher mortality than other hospitals (11.2% versus 8.7%; RR=1.29; 95% CI 1.04 to 1.59).
Paradoxically, hospitals with a history of zero mortality subsequently experience mortality rates that are the same or higher than those of other hospitals. Patients considering surgery should not consider a reported mortality of zero as being a reliable indicator of future performance.
考虑到何处进行手术的患者可能会合理地认为,在报告手术死亡率为零的医院,其生存几率最高。我们试图确定在3年期间死亡率为零的医院在随后一年的死亡率是否也低于平均水平。
我们获取了国家医疗保险关于五种手术死亡率较高(>4.0%)的数据:冠状动脉搭桥术、腹主动脉瘤修复术以及结肠癌、肺癌和胰腺癌切除术。对于每种手术,我们将死亡率为零的医院定义为在1997年至1999年3年期间没有住院患者死亡或30天内死亡的医院。为了确定这些医院的死亡率是否实际上低于其他医院,我们将它们在次年(2000年)的死亡率与所有其他医院的死亡率进行了比较。
对于四种手术,死亡率为零的医院在随后一年的手术死亡率与其他医院没有差异:腹主动脉瘤修复术(死亡率为零的医院为6.3%,其他医院为5.8%;调整后的相对风险[RR]=1.09;95%置信区间0.92至1.29);肺癌肺叶切除术(5.1%对5.3%;RR=0.96;95%置信区间0.80至1.15);结肠癌切除术(6.0%对6.6%;RR=0.91;95%置信区间0.80至1.03);以及冠状动脉搭桥手术(4.0%对5.0%;RR=0.81;95%置信区间0.61至1.04)。在胰腺癌切除术方面,死亡率为零的医院的死亡率显著高于其他医院(11.2%对8.7%;RR=1.29;95%置信区间1.04至1.59)。
矛盾的是,有死亡率为零历史的医院随后的死亡率与其他医院相同或更高。考虑手术的患者不应将报告的死亡率为零视为未来表现的可靠指标。