Stawicki S Peter, Seamon Mark J, Kim Patrick K, Meredith Denise M, Chovanes John, Schwab C William, Gracias Vicente H
Department of Surgery, Division of Traumatology and Surgical Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
J Am Coll Surg. 2008 Jan;206(1):42-7. doi: 10.1016/j.jamcollsurg.2007.06.293. Epub 2007 Sep 17.
Use of transthoracic echocardiography (TTE) in documenting cardiac disorders is well accepted. This study reviews institutional experience with TTE in the clinical setting of pulmonary embolism (PE).
Retrospective review of surgical ICU patients who underwent TTE within 72 hours of diagnosis of PE, from January 2005 to March 2007. Collected data included symptoms, clinical suspicion of PE, preexisting conditions, operative procedures, TTE findings, presence of deep venous thrombosis, and treatments used for PE. Preexisting TTEs, when available, were compared with those obtained after acute PE. TTEs subsequent to the first post-PE study were analyzed for change in severity of findings.
Thirty-one patients (12 men, 19 women, mean age 66 years, APACHE II 18.1) were included. Twenty-two had high, and nine had moderate, clinical suspicion for PE. Radiographic diagnosis of PE was made by computed tomography (25 of 31) and by ventilation-perfusion scans (6 of 31). Twelve of 31 patients had extremity deep venous thrombosis by duplex ultrasonography. Tricuspid regurgitation was the most common TTE finding (28 of 31), followed by pulmonary hypertension (24), dilated right ventricle (23), right heart strain (19), and underfilled, hyperdynamic left ventricle (17). Seventeen patients had previous or "baseline" echocardiograms, and when compared with the post-PE TTE, all patients demonstrated worsening in at least one TTE finding.
This study identified findings that can be used in prospective evaluation of TTE for suspected PE. The importance of baseline TTE has also been emphasized. Additional prospective evaluation of TTE in diagnosis of suspected PE in the ICU is warranted.
经胸超声心动图(TTE)用于记录心脏疾病已被广泛接受。本研究回顾了在肺栓塞(PE)临床环境中使用TTE的机构经验。
对2005年1月至2007年3月期间在诊断为PE后72小时内接受TTE检查的外科重症监护病房患者进行回顾性研究。收集的数据包括症状、对PE的临床怀疑、既往病史、手术操作、TTE检查结果、深静脉血栓形成情况以及用于PE的治疗方法。如有既往TTE检查结果,将其与急性PE发作后获得的结果进行比较。对首次PE发作后TTE检查结果进行后续分析,以观察检查结果严重程度的变化。
纳入31例患者(12例男性,19例女性,平均年龄66岁,急性生理与慢性健康状况评分系统II评分为18.1)。22例临床高度怀疑PE,9例临床中度怀疑PE。通过计算机断层扫描(31例中的25例)和通气-灌注扫描(31例中的6例)进行PE的影像学诊断。31例患者中有12例经双功超声检查发现肢体深静脉血栓形成。三尖瓣反流是最常见的TTE检查结果(31例中的28例),其次是肺动脉高压(24例)、右心室扩张(23例)、右心劳损(19例)以及左心室充盈不足、动力增强(17例)。17例患者有既往或“基线”超声心动图检查结果,与PE发作后的TTE检查结果相比,所有患者至少有一项TTE检查结果恶化。
本研究确定了可用于对疑似PE进行TTE前瞻性评估的检查结果。还强调了基线TTE的重要性。有必要对ICU中疑似PE诊断的TTE进行进一步前瞻性评估。