Kim Eun-Cheol, Lee Byung-Cheon, Chang Hoon-Sang, Lee Wan, Hong Chan-Ui, Min Kyung-San
Department of Oral and Maxillofacial Pathology, College of Dentistry, Wonkwang University, Iksan, Republic of Korea.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jan;105(1):e54-7. doi: 10.1016/j.tripleo.2007.08.001.
This study aimed at evaluating the radiopacity and cytotoxicity of Portland cements containing bismuth oxide (PcBo) in varying ratios.
Specimens measuring 10 mm in diameter and 1 mm in thickness were radiographed with an aluminum step wedge using an occlusal film. The radiographs were digitized, and the radiopacity of each material was compared to the different thicknesses of the aluminum step wedge. Using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, the cytotoxicity of each material was determined in immortalized human periodontal ligament (IPDL) cells.
The results demonstrated that Portland cement with 20% bismuth oxide presented greater radiopacity (P < .05) compared to the mixtures with less bismuth oxide. The cell viabilities of all PcBo groups were statistically similar (P > .05) throughout the experimental period.
These results indicate that Portland cement with 20% bismuth oxide has a greater potential for being used as a root-end filling material compared to Portland cement with less bismuth oxide.
本研究旨在评估不同比例含氧化铋的波特兰水泥（PcBo）的射线不透性和细胞毒性。
使用咬合片，对直径10毫米、厚度1毫米的样本与铝阶梯楔形块进行射线照相。将射线照片数字化，并将每种材料的射线不透性与铝阶梯楔形块的不同厚度进行比较。使用3-(4,5-二甲基噻唑-2-基)-2,5-二苯基四氮唑溴盐（MTT）法，在永生化人牙周膜（IPDL）细胞中测定每种材料的细胞毒性。
结果表明，与含较少氧化铋的混合物相比，含20%氧化铋的波特兰水泥具有更高的射线不透性（P < .05）。在整个实验期间，所有PcBo组的细胞活力在统计学上相似（P > .05）。
这些结果表明，与含较少氧化铋的波特兰水泥相比，含20%氧化铋的波特兰水泥作为根尖充填材料具有更大的潜力。
