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他汀类药物相关的局灶性肌炎。

Statin-associated focal myositis.

作者信息

Asbach Patrick, Paetsch Ingo, Stawowy Philipp, Sander Bernhard, Fleck Eckart

出版信息

Int J Cardiol. 2009 Mar 20;133(1):e33-4. doi: 10.1016/j.ijcard.2007.08.109. Epub 2007 Dec 26.

DOI:10.1016/j.ijcard.2007.08.109
PMID:18155787
Abstract

Myositis is an infrequent side effect of statin therapy, usually presenting as diffuse myositis with muscle weakness and cramping involving multiple body parts. We report a case of focal myositis of a hip muscle diagnosed on magnetic resonance imaging, as the underlying pathology was suspected to be related to an orthopaedic disease due to isolated hip symptoms, and which was finally attributed to statin intake. Awareness to this rare cause of musculoskeletal symptoms is indicated in case a patient presents with probable orthopaedic disease and is on statin therapy.

摘要

肌炎是他汀类药物治疗罕见的副作用,通常表现为弥漫性肌炎,伴有肌肉无力和痉挛,累及身体多个部位。我们报告一例通过磁共振成像诊断的髋部肌肉局灶性肌炎病例,由于孤立的髋部症状,其潜在病理被怀疑与一种骨科疾病有关,最终归因于他汀类药物的摄入。如果患者患有可能的骨科疾病且正在接受他汀类药物治疗,应注意这种导致肌肉骨骼症状的罕见原因。

相似文献

1
Statin-associated focal myositis.他汀类药物相关的局灶性肌炎。
Int J Cardiol. 2009 Mar 20;133(1):e33-4. doi: 10.1016/j.ijcard.2007.08.109. Epub 2007 Dec 26.
2
Statin-induced focal myositis of the upper extremity. A report of two cases.他汀类药物引起的上肢局灶性肌炎。两例报告。
Eur J Radiol. 2011 Feb;77(2):258-60. doi: 10.1016/j.ejrad.2010.12.031. Epub 2011 Jan 12.
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Statin-induced muscular symptoms: a report of 3 cases.他汀类药物引起的肌肉症状:3例报告
Acta Orthop Belg. 2008 Aug;74(4):569-72.
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Presymptomatic neuromuscular disorders disclosed following statin treatment.他汀类药物治疗后发现的症状前神经肌肉疾病。
Arch Intern Med. 2006 Jul 24;166(14):1519-24. doi: 10.1001/archinte.166.14.1519.
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Genetic determinants of statin intolerance.他汀类药物不耐受的遗传决定因素。
Lipids Health Dis. 2007 Mar 21;6:7. doi: 10.1186/1476-511X-6-7.
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Unrecognized side effect of statin treatment: unilateral blepharoptosis.
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Hyaline inclusion myopathy: unmasked by statin therapy.透明质酸包涵体肌病:由他汀类药物治疗所揭示。
Muscle Nerve. 2009 Oct;40(4):657-61. doi: 10.1002/mus.21079.
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Is statin-induced myositis part of the polymyositis disease spectrum?他汀类药物诱导的肌炎是多肌炎疾病谱的一部分吗?
Curr Rheumatol Rep. 2014 Aug;16(8):433. doi: 10.1007/s11926-014-0433-8.
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Sudden proximal paraparesis secondary to statin myositis.
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[Focal myositis--an indication for surgery? A case report].[局灶性肌炎——手术指征?一例病例报告]
Chirurg. 2002 Oct;73(10):1063-6. doi: 10.1007/s00104-002-0508-3.

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A Patient With Focal Myositis and Primary Cutaneous Diffuse Large B-Cell Lymphoma: A Case Report.一名患有局灶性肌炎和原发性皮肤弥漫性大B细胞淋巴瘤的患者:病例报告
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Statin therapy decreases myocardial function as evaluated via strain imaging.他汀类药物治疗可通过应变成像评估降低心肌功能。
Clin Cardiol. 2009 Dec;32(12):684-9. doi: 10.1002/clc.20644.
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Use of an electronic medical record to characterize cases of intermediate statin-induced muscle toxicity.利用电子病历对他汀类药物所致中度肌肉毒性病例进行特征分析。
Prev Cardiol. 2009 Spring;12(2):88-94. doi: 10.1111/j.1751-7141.2009.00028.x.