Gleizal Arnaud, Torossian Jean Marc, Wan Derrick C, Béziat Jean-Luc
Department of Maxillofacial Surgery, Université Claude Bernard Lyon 1, France. arnaud.gleizal@chu-lyon
Br J Oral Maxillofac Surg. 2008 Jul;46(5):416-8. doi: 10.1016/j.bjoms.2007.10.006. Epub 2007 Dec 26.
Testicular choriocarcinoma is a highly malignant germ cell neoplasm, which metastasises to lungs, and brain. Spread to the skin, however, is rare, with only 11 cases reported to our knowledge. This is the second reported case of a skin metastasis of choriocarcinoma to the head and neck, and the third in which a cutaneous metastasis was the first finding at initial presentation. A review of published reports showed that it had been described as individual firm, reddish or violaceous subcutaneous nodules with typical histological features.
睾丸绒毛膜癌是一种高度恶性的生殖细胞肿瘤,可转移至肺和脑。然而,其转移至皮肤的情况罕见,据我们所知仅有11例报告。这是第二例报告的绒毛膜癌转移至头颈部皮肤的病例,也是第三例以皮肤转移为首次就诊时首发表现的病例。对已发表报告的回顾显示,它被描述为具有典型组织学特征的单个坚实、红色或紫色皮下结节。