Oliveira Mariana G, Silveira Rita C, Procianoy Renato S
Department of Pediatrics, Newborn Section, Universidade Federal do Rio Grande do Sul and Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
J Trop Pediatr. 2008 Feb;54(1):36-42. doi: 10.1093/tropej/fmm103. Epub 2007 Dec 21.
The objective of this article is to describe growth of very low birth weight infants born in southern Brazil. All infants weighing < or =1500 g were followed up until 12 months corrected age (CA). Growth was recorded at 40 weeks, 6 and 12 months CA. Catch up was considered if the measures were > or =-2 SD of World Health Organization growth charts for weight and length; and of National Center for Health Statistics for head circumference. One hundred and ninety three infants born were followed up for the study. At 40 weeks CA, 57.8% patients achieved catch-up in weight and 50.9% in length. At 6 months CA, 82.2% achieved catch-up for weight and length and at 1 year CA, 92% achieved catch-up in weight and 86.9% in length. Catch-up in head circumference was achieved for 93.4%, 85.9% and 85% patients at 40 weeks, 6 months and 12 months CA, respectively. At 12 months CA, no catch-up in weight, length and head circumference was related to higher SNAPPE-II (P = 0.046) and periventricular leukomalacia (PVL) (P = 0.003); longer time to achieve full enteral nutrition at the neonatal intensive care unit (NICU) (P = 0.037), lower maternal education (P = 0.018) and PVL (P = 0,003); higher SNAPPE-II (P = 0,004), PVL (P = 0.005) and longer time to achieve full enteral nutrition at the NICU (P = 0.044), respectively. In conclusion, PVL and higher SNAPPE-II were important factors to catch-up delay. Catch-up growth was high at 12 months CA.
本文的目的是描述巴西南部出生的极低出生体重儿的生长情况。所有体重≤1500克的婴儿均随访至矫正年龄(CA)12个月。在矫正年龄40周、6个月和12个月时记录生长情况。如果测量值≥世界卫生组织生长图表中体重和身长的-2标准差,以及美国国家卫生统计中心头围的-2标准差,则认为实现了追赶生长。193名出生婴儿纳入本研究随访。在矫正年龄40周时,57.8%的患者体重实现追赶生长,50.9%的患者身长实现追赶生长。在矫正年龄6个月时,82.2%的患者体重和身长实现追赶生长;在矫正年龄1岁时,92%的患者体重实现追赶生长,86.9%的患者身长实现追赶生长。在矫正年龄40周、6个月和12个月时,分别有93.4%、85.9%和85%的患者头围实现追赶生长。在矫正年龄12个月时,体重、身长和头围未实现追赶生长与较高的SNAPPE-II评分(P = 0.046)和脑室周围白质软化(PVL)(P = 0.003)有关;在新生儿重症监护病房(NICU)达到完全肠内营养的时间较长(P = 0.037)、母亲受教育程度较低(P = 0.018)以及PVL(P = 0.003);分别与较高的SNAPPE-II评分(P = 0.004)、PVL(P = 0.005)以及在NICU达到完全肠内营养的时间较长(P = 0.044)有关。总之,PVL和较高的SNAPPE-II评分是追赶生长延迟的重要因素。在矫正年龄12个月时追赶生长情况良好。