Kim Han Sung, Cho Hyoun Chan, Kim Sun Hee, Moon Yeonsook, Nahm Chung Hyun, Choi Jong Weon, Kim Jin Ju
Department of Laboratory Medicine, Hallym University College of Medicine, Anyang, Korea.
Korean J Lab Med. 2006 Aug;26(4):246-8. doi: 10.3343/kjlm.2006.26.4.246.
We report a case of chronic myelogenous leukemia displaying a variant Philadelphia translocation t(11;22)(q25;q11.2). Breakpoint 11q25 has not previously been reported. Reverse transcriptase polymerase chain reaction and fluorescence in-situ hybridization demonstrated the BCR/ABL rearrangement.
我们报告一例慢性粒细胞白血病,其显示出一种变异的费城染色体易位t(11;22)(q25;q11.2)。11q25断点此前未见报道。逆转录聚合酶链反应和荧光原位杂交证实了BCR/ABL重排。