Guimarães Raphael Mendonça, Asmus Carmen Ildes Rodrigues Fróes, Meyer Armando
Instituto de Estudos em Saúde Coletiva, Universidade Federal do Rio de Janeiro, Avenida Brigadeiro Trompowski s/n, Rio de Janeiro, Brazil.
Cad Saude Publica. 2007 Dec;23(12):2835-44. doi: 10.1590/s0102-311x2007001200004.
DDT is a persistent insecticide that was widely used in the world from the 1940s until the 70s, when it was banned in the United States and other countries. Most of its toxic effects are not observed in the acute forms, but particularly after chronic exposure. These long-term issues include reproductive effects, varying according to the time of life in which the individuals were exposed. The aims of the current study were to review the principal toxicological effects of DDT on reproduction, stratifying by physiological periods of exposure, and based on the magnitude of these effects, to discuss the cost-benefit relationship of reintroducing DDT with the specifically defined vector control criteria.
滴滴涕是一种持久性杀虫剂，从20世纪40年代到70年代在世界范围内广泛使用，70年代在美国和其他国家被禁用。其大多数毒性作用并非以急性形式表现出来，而是尤其在长期接触后才显现。这些长期问题包括生殖方面的影响，其会因个体接触滴滴涕的生命阶段不同而有所差异。本研究的目的是回顾滴滴涕对生殖的主要毒理学影响，按接触的生理时期进行分层，并基于这些影响的程度，讨论在特定的病媒控制标准下重新引入滴滴涕的成本效益关系。
