从一个疟疾媒介控制地区采集的大鼠肝脏中的滴滴涕（DDT）含量。
Dichlorodiphenyltrichloroethane (DDT) levels in rat livers collected from a malaria vector control region.
作者信息
Motohira Kodai, Ikenaka Yoshinori, Yohannes Yared Beyene, Nakayama Shouta M M, Wepener Victor, Smit Nico J, VAN Vuren Johan H J, Sousa Ana Catarina, Enuneku Alex Ajeh, Ogbomida Emmanuel Temiotan, Ishizuka Mayumi
机构信息
Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Laboratory of Toxicology, Hokkaido University, Kita 18, Nishi 9, Kita-ku, Sapporo, Hokkaido 060-0818, Japan.
Water Research Group, Unit for Environmental Sciences and Management, Potchefstroom Campus, North-West University, Private Bag X6001, Potchefstroom, South Africa.
出版信息
J Vet Med Sci. 2019 Nov 14;81(11):1575-1579. doi: 10.1292/jvms.19-0168. Epub 2019 Aug 23.
Dichlorodiphenyltrichloroethane (DDT) is an organochlorine insecticide that has been used for indoor residual spraying for the control of mosquito-borne diseases including malaria. However, due to its toxicity and environmental persistence, there are concerns about its potential deleterious effects in humans and wildlife. Therefore, the current study aimed to monitor and estimate the level of DDTs in human communities. The accumulation of DDT and its metabolites was evaluated in house rat (as sentinel) livers collected in an area where DDT was sprayed. DDTs were measured using a gas chromatography / Electron Capture Detector. The results revealed high concentrations of DDTs in the rat livers and the levels of DDTs were similar to findings reported from the same area in 2014.
滴滴涕（DDT）是一种有机氯杀虫剂，曾被用于室内残留喷洒，以控制包括疟疾在内的蚊媒疾病。然而，由于其毒性和环境持久性，人们担心它对人类和野生动物可能产生有害影响。因此，本研究旨在监测和评估人类社区中滴滴涕的含量水平。在喷洒过滴滴涕的地区收集家鼠（作为哨兵动物）肝脏，评估滴滴涕及其代谢物的蓄积情况。使用气相色谱/电子捕获检测器测量滴滴涕。结果显示，大鼠肝脏中滴滴涕浓度很高，且滴滴涕水平与2014年该地区报告的结果相似。
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