Byard R W, Bourne A J, Hanieh A
Department of Histopathology, Adelaide Children's Hospital, Australia.
Pediatr Neurosurg. 1991;17(2):88-94. doi: 10.1159/000120573.
A retrospective review of the Department of Histopathology files at the Adelaide Children's Hospital was conducted to examine all cases where sudden death (defined as death occurring within 24 h of sudden collapse and unconsciousness in a previously apparently well child) was attributable to hemorrhage from an occult central nervous system lesion. Ten cases were found with significant hemorrhage and associated cerebral edema. The diagnoses were cerebral arteriovenous malformation (1), probable cerebellar vascular malformation (4), berry aneurysm of middle cerebral artery (1), cerebellar medulloblastoma (1), optic chiasm astrocytoma (1), pineal gland teratoma (1), and fourth ventricle ependymoma (1). These cases demonstrate the wide range and variable location of intracranial lesions capable of causing sudden death in children. Careful examination of the brain in all cases of sudden pediatric death is essential so that intracranial lesions causing unexpected death will be adequately characterized.
对阿德莱德儿童医院组织病理学档案进行了回顾性研究，以检查所有因隐匿性中枢神经系统病变出血导致猝死（定义为先前看似健康的儿童突然晕倒并失去意识后24小时内死亡）的病例。发现10例有明显出血及相关脑水肿。诊断包括脑动静脉畸形（1例）、可能的小脑血管畸形（4例）、大脑中动脉浆果样动脉瘤（1例）、小脑髓母细胞瘤（1例）、视交叉星形细胞瘤（1例）、松果体畸胎瘤（1例）和第四脑室室管膜瘤（1例）。这些病例表明，能够导致儿童猝死的颅内病变范围广泛且位置各异。对所有儿童猝死病例进行仔细的脑部检查至关重要，以便充分明确导致意外死亡的颅内病变特征。
