O'Toole Brian I, Catts Stanley V
ANZAC Research Institute, University of Sydney, Australia.
J Psychosom Res. 2008 Jan;64(1):33-40. doi: 10.1016/j.jpsychores.2007.07.006.
This study aimed to examine the relative contributions to physical health of combat trauma exposure and posttraumatic stress disorder (PTSD), which have both been implicated separately in poorer physical health but whose unconfounded effects have not been teased out.
Data from an epidemiological study of Australian Vietnam veterans, which used personal interviews and standardized physical and psychiatric health assessments, provided the means to assess the independent and joint effects of psychological trauma exposure and PTSD on a wide range of self-reported measures of physical health. Trauma exposure was measured by published scales of combat exposure and peritraumatic dissociation. Logistic regression modeling was used to assess the relative importance of trauma exposure and PTSD to health while controlling for a set of potential confounders including standardized psychiatric diagnoses.
Greater health service usage and more recent health actions were associated more strongly with PTSD, which was also associated with a range of illness conditions coded by the World Health Organization International Classification of Diseases, 9th Edition (asthma, eczema, arthritis, back and other musculoskeletal disorders, and hypertension) both before and after controlling for potential confounders. In contrast, combat exposure and peritraumatic dissociation were more weakly associated with a limited number of unconfounded physical health outcomes.
This study provided evidence that PTSD, rather than combat exposure and peritraumatic dissociation, is associated with a pattern of physical health outcomes that is consistent with altered inflammatory responsiveness.
本研究旨在探讨战斗创伤暴露和创伤后应激障碍(PTSD)对身体健康的相对影响,这两者均被认为与较差的身体健康状况分别相关,但它们的独立影响尚未得到明确区分。
来自一项对澳大利亚越战退伍军人的流行病学研究的数据,该研究采用个人访谈以及标准化的身体和精神健康评估,为评估心理创伤暴露和PTSD对一系列自我报告的身体健康指标的独立及联合影响提供了途径。创伤暴露通过已发表的战斗暴露量表和创伤周围解离量表进行测量。在控制包括标准化精神诊断在内的一组潜在混杂因素的同时,使用逻辑回归模型评估创伤暴露和PTSD对健康的相对重要性。
更多的医疗服务使用和更近的健康行为与PTSD的关联更强,在控制潜在混杂因素前后,PTSD还与世界卫生组织《国际疾病分类》第9版编码的一系列疾病状况(哮喘、湿疹、关节炎、背部和其他肌肉骨骼疾病以及高血压)相关。相比之下,战斗暴露和创伤周围解离与数量有限的无混杂因素的身体健康结果的关联较弱。
本研究提供的证据表明,与身体健康结果模式相关的是PTSD,而非战斗暴露和创伤周围解离,这种模式与炎症反应性改变一致。