Kwak Soo-Yeong, Gwak Geum-Youn, Yun Won-Kyoung, Kim Hyo-Jin, Do In Gu, Joh Jae-Won, Park Cheol-Keun
Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Korean J Hepatol. 2007 Dec;13(4):560-4. doi: 10.3350/kjhep.2007.13.4.560.
A 46-year-old woman was found to have a huge liver mass that was detected by abdominal ultrasonography. Abdominal CT and MRI showed a 10 cm-sized, encapsulated mass occupying the anterior segment of the right hepatic lobe. Extended right hemihepatectomy was performed and pathological examination revealed fibroblast-like spindle cells within dense deposits of collagen. On immunohistochemical staining, these spindle tumor cells showed an intense CD34 immunoreactivity. The patient is alive without evidence of tumor recurrence 7 months after the resection. Solitary fibrous tumor is a very rare neoplasm found in the liver parenchyma, and it has been reported in less than 30 patients in the English literature. We present here the first such case in Korea.
一名46岁女性经腹部超声检查发现肝脏有巨大肿块。腹部CT和MRI显示一个10厘米大小的、有包膜的肿块,占据右肝叶前段。实施了扩大右半肝切除术,病理检查显示在致密的胶原沉积中有成纤维细胞样梭形细胞。免疫组化染色显示,这些梭形肿瘤细胞呈现强烈的CD34免疫反应性。该患者在切除术后7个月仍存活,无肿瘤复发迹象。孤立性纤维瘤是一种在肝实质中发现的非常罕见的肿瘤,英文文献中报道的患者不到30例。我们在此呈现韩国首例此类病例。