Loutfy Mona R, Austin John W, Blanchfield Burke, Fong Ignatius W
Department of Medicine, University of Toronto, Toronto, Ontario.
Can J Infect Dis. 2003 Jul;14(4):206-9. doi: 10.1155/2003/601525.
Botulism is a rare paralytic illness resulting from a potent neurotoxin produced by Clostridium botulinum. Botulism in Canada is predominately due to C botulinum type E and affects mainly the First Nations and Inuit populations. The most recent outbreak of botulism in Ontario was in Ottawa in 1991 and was caused by C botulinum type A. We report an outbreak of foodborne type B botulism in Ontario, which implicated home-canned tomatoes. The outbreak was characterized by mild symptoms in two cases and moderately severe illness in one case. The investigation shows the importance of considering the diagnosis of botulism in patients presenting with cranial nerve and autonomic dysfunction, especially when combined with gastrointestinal complaints; it also highlights the importance of proper home canning technique.
肉毒中毒是一种由肉毒梭菌产生的强效神经毒素引起的罕见麻痹性疾病。加拿大的肉毒中毒主要由E型肉毒梭菌引起,主要影响原住民和因纽特人群体。安大略省最近一次肉毒中毒疫情发生在1991年的渥太华,由A型肉毒梭菌引起。我们报告了安大略省一起食源性B型肉毒中毒疫情,涉及家庭自制罐装番茄。此次疫情的特点是两例症状较轻,一例病情为中度严重。调查表明,对于出现颅神经和自主神经功能障碍的患者,尤其是伴有胃肠道不适时,考虑肉毒中毒诊断的重要性;同时也凸显了正确家庭罐装技术的重要性。