细菌性阴道病的实验室诊断。
The laboratory diagnosis of bacterial vaginosis.
机构信息
Maternal & Fetal Medicine, Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia.
出版信息
Can J Infect Dis Med Microbiol. 2005 Mar;16(2):77-9. doi: 10.1155/2005/230319.
Abstract
Bacterial vaginosis (BV) is an extremely common health problem for women. In addition to the troublesome symptoms often associated with a disruption in the balance of vaginal flora, BV is associated with adverse gynecological and pregnancy outcomes. Although not technically a sexually transmitted infection, BV is a sexually associated condition. Diagnostic tests include real-time clinical/microbiological diagnosis, and the current gold standard, the standardized evaluation of morphotypes on Gram stain analysis. The inappropriate use of vaginal culture can be misleading. Future developments into molecular-based diagnostics will be important to further understand this complex endogenous flora disruption.
摘要
细菌性阴道病（BV）是女性极为常见的健康问题。除了与阴道菌群失衡相关的常见症状外，BV 还与不良的妇科和妊娠结局相关。虽然从技术上讲，BV 不是一种性传播感染，但它是一种与性行为相关的疾病。诊断测试包括实时临床/微生物学诊断，以及目前的金标准，即革兰氏染色分析中对形态的标准化评估。阴道培养的不当使用可能会产生误导。基于分子的诊断学的未来发展对于进一步了解这种复杂的内源性菌群紊乱将很重要。
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本文引用的文献
1
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Microbiology (Reading). 2004 Aug;150(Pt 8):2565-2573. doi: 10.1099/mic.0.26905-0.
2
Gynecologic consequences of bacterial vaginosis.
Obstet Gynecol Clin North Am. 2003 Dec;30(4):685-94. doi: 10.1016/s0889-8545(03)00086-x.
3
Haemophilus vaginalis vaginitis: a newly defined specific infection previously classified non-specific vaginitis.阴道嗜血杆菌性阴道炎：一种先前归类为非特异性阴道炎的新定义的特定感染。
Am J Obstet Gynecol. 1955 May;69(5):962-76.
4
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Obstet Gynecol. 2002 Oct;100(4):759-64. doi: 10.1016/s0029-7844(02)02201-9.
5
Preventing adverse sequelae of bacterial vaginosis: a public health program and research agenda.
Sex Transm Dis. 2001 May;28(5):292-7. doi: 10.1097/00007435-200105000-00011.
6
Gram-stain diagnosis of bacterial vaginosis after rupture of membranes.
Am J Perinatol. 2000;17(6):315-8. doi: 10.1055/s-2000-13442.
7
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Obstet Gynecol. 2000 Oct;96(4):504-6. doi: 10.1016/s0029-7844(00)00994-7.
8
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9
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Int J STD AIDS. 1999 Feb;10(2):93-7. doi: 10.1258/0956462991913709.
10
Gram stain method shows better sensitivity than clinical criteria for detection of bacterial vaginosis in surveillance of pregnant, low-income women in a clinical setting.在临床环境中对低收入孕妇进行细菌性阴道病监测时，革兰氏染色法在检测细菌性阴道病方面比临床标准显示出更高的敏感性。
Infect Dis Obstet Gynecol. 1998;6(5):204-8. doi: 10.1002/(SICI)1098-0997(1998)6:5<204::AID-IDOG3>3.0.CO;2-R.
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