Gex Grégoire, Janssens Jean-Paul
Service de médecine interne générale, HUG, Genève.
Rev Med Suisse. 2007 Nov 21;3(134):2646, 2648-50, 2652-4.
Two studies showed that continuous long-term oxygen therapy (> 15 h/d) undoubtedly confers a significant benefit on survival in hypoxemic patients with chronic obstructive pulmonary disease. This treatment should be prescribed to stable patients with a PaO2 < 7.3 kPa or a PaO2 < 8 kPa and either previous episodes of ankle edema, pulmonary hypertension or a haematocrit > 55%. Patients who are hypoxemic only during exercise can also benefit from mobile oxygen therapy. However, the Swiss Society of Pneumology does not recommend treating patients with isolated nocturnal hypoxemia, unless they suffer from central apnea and are shown to be responders. The characteristics of the three methods of oxygen delivery for domiciliary treatment are discussed in this review.
两项研究表明，持续长期氧疗（>15小时/天）无疑能给慢性阻塞性肺疾病低氧血症患者的生存带来显著益处。对于PaO2 < 7.3 kPa或PaO2 < 8 kPa且有既往踝部水肿、肺动脉高压发作史或血细胞比容> 55%的稳定患者，应给予这种治疗。仅在运动时出现低氧血症的患者也可从便携式氧疗中获益。然而，瑞士肺病学会不建议治疗单纯夜间低氧血症患者，除非他们患有中枢性呼吸暂停且被证明有反应。本综述讨论了家庭治疗的三种氧输送方法的特点。
