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[咽旁间隙肌上皮癌的影像学表现及临床病理特征]

[Image date and clinicopathologic features of myoepithelial carcinoma in parapharyngeal space].

作者信息

Fu Min, Wang Xiaobing, Wu Peina, Luo Xiaoning

机构信息

Department of Otorhinolaryngology, Guangdong Provincial People's Hospital, Guangzhou, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2007 Oct;21(19):879-81.

PMID:18159768
Abstract

OBJECTIVE

To study the image data and clinicopathologic features of myoepithelial carcinoma in parapharyngeal space.

METHOD

Based on one patient with myoepithelial carcinoma of parapharyngeal space treated in our hospital, image data and clinicopathologic findings were analyzed. The clinical characteristics of myoepithelial carcinoma in head and neck region were discussed.

RESULT

CT obviously showed the mass in parapharyngeal space with destruction of temporal bone. Immunohistochemical stain showed positive staining for S-100 protein, Smooth muscle actin, Cytokeratin and Vimentin. There were otalgia, bloody pus, headache and signs of cranial nerve lesion.

CONCLUSION

Myoepithelial carcinoma was a rare malignant epithelial neoplasm and had a poor prognosis. Myoepithelial carcinoma often occurrence in salivary gland of maxillofacial region. The clinical signs were otalgia and headache in patient with myoepithelial carcinoma in parapharyngeal space. CT image showed malignant neoplasm and surrounding tissues were destroyed. Diagnosis depends on pathology and immunohistochemistry.

摘要

目的

研究咽旁间隙肌上皮癌的影像资料及临床病理特征。

方法

基于我院收治的1例咽旁间隙肌上皮癌患者,分析其影像资料及临床病理表现。探讨头颈部肌上皮癌的临床特点。

结果

CT明显显示咽旁间隙肿物并伴有颞骨破坏。免疫组化染色显示S-100蛋白、平滑肌肌动蛋白、细胞角蛋白和波形蛋白呈阳性染色。患者有耳痛、脓血、头痛及脑神经损害体征。

结论

肌上皮癌是一种罕见的恶性上皮性肿瘤,预后较差。肌上皮癌常发生于颌面区域的涎腺。咽旁间隙肌上皮癌患者的临床症状为耳痛和头痛。CT影像显示为恶性肿瘤且周围组织被破坏。诊断依靠病理及免疫组化。

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