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[鼻腔发生的上皮-肌上皮癌:一例报告及文献复习]

[Epithelial-myoepithelial carcinoma arising in the nasal cavity: a case report and literature review].

作者信息

Ye Zhiteng, Guo Yongqing

机构信息

Department of Otorhinolaryngology, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, 361004, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012 Dec;26(23):1092-4.

Abstract

OBJECTIVE

To seek pathological features, diagnosis, treatment, prognosis of Epithelial-myoepithelial carcinoma arising in the nasal cavity.

METHOD

One case of Epithelial-myoepithelial carcinoma arising in the nasal cavity was analyzed retrospectively and studied with immunohistochemical Staining and light microscopy, as well as review of the literature.

RESULT

The clinical feature of epithelial-myoepithelial carcinoma in the nasal cavity was atypical and diagnosis relied on pathologic features. Epithelial-myoepithelial carcinoma consisted of myoepithelial and epithelial cells. Immunohistochemical staining demonstrated that cytokeratin P, cytokeratin L, S-100 protein, a-smooth muscle actin expressed positively.

CONCLUSION

Epithelial-myoepithelial carcinoma in the nasal cavity is a rare neoplasm. Wide surgical excision with a clear margin is the main therapy,and these tumors have the potential for metastasis and recurrence.

摘要

目的

探寻鼻腔上皮-肌上皮癌的病理特征、诊断、治疗及预后情况。

方法

回顾性分析1例鼻腔上皮-肌上皮癌病例,采用免疫组织化学染色及光学显微镜检查,并复习相关文献。

结果

鼻腔上皮-肌上皮癌的临床特征不典型,诊断依赖病理特征。上皮-肌上皮癌由肌上皮细胞和上皮细胞组成。免疫组织化学染色显示细胞角蛋白P、细胞角蛋白L、S-100蛋白、α-平滑肌肌动蛋白呈阳性表达。

结论

鼻腔上皮-肌上皮癌是一种罕见肿瘤。手术切缘清晰的广泛切除是主要治疗方法,这些肿瘤有转移和复发的可能。

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