Husson M O, Vincent P, Grabiaud M H, Furon D, Leclerc H
Institut National de la Santé et de la Recherche Médicale, Unité 146, Villeneuve d'Ascq, France.
Gastroenterol Clin Biol. 1991;15(10):723-6.
The aim of our study was to detect antibodies against Helicobacter pylori (H. pylori) in abattoir workers whose activity was variable (pig, poultry-carcasses, poultry-intestinal organs treatment). An adsorption of all sera with H. pylori and Campylobacter species known to be ubiquitous and responsible for zoonosis was included in the ELISA reaction to eliminate possible cross-reactions between these species. Statistically higher specific titres of IgG antibodies against H. pylori were observed in men and women who had only worked for 1 or 2 years versus matched controls, indicating a possible transmission of H. pylori from animal to man. The role of poultry or pigs as contaminants alone or in association remains to be determined.
我们研究的目的是检测屠宰场工人（其工作涉及多种类型，包括猪、家禽屠体、家禽内脏处理）体内针对幽门螺杆菌（H. pylori）的抗体。在酶联免疫吸附测定（ELISA）反应中，所有血清均用已知普遍存在且可导致人畜共患病的幽门螺杆菌和弯曲杆菌属细菌进行吸附，以消除这些菌种之间可能的交叉反应。与匹配的对照组相比，仅工作1年或2年的男性和女性体内针对幽门螺杆菌的IgG抗体特异性滴度在统计学上更高，这表明幽门螺杆菌可能从动物传播给人类。家禽或猪单独或联合作为传染源的作用仍有待确定。
