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在临床实践中控制糖尿病的基本要素:基于社区的内分泌科实践经验

Controlling the ABCs of diabetes in clinical practice: a community-based endocrinology practice experience.

作者信息

Varma Swarna, Boyle Laura L, Varma Manu R, Piatt Gretchen A

机构信息

Pittsburgh Endocrinology and Diabetes Associates, Bridgeville, PA 15017, USA.

出版信息

Diabetes Res Clin Pract. 2008 Apr;80(1):89-95. doi: 10.1016/j.diabres.2007.10.029. Epub 2007 Dec 21.

DOI:10.1016/j.diabres.2007.10.029
PMID:18160171
Abstract

AIMS

Determine A1C, blood pressure (BP), and total cholesterol (TC) (Diabetes ABCs) control in a community-based endocrinology practice (CBEP) and compare levels to national averages. Additionally, determine patient factors associated with ABC control.

METHODS

A retrospective chart audit of 395 consecutive patients seen for diabetes management was conducted for years 2000-2004 to examine levels of control of the ABCs. Multivariate models were used to determine patient factors associated with control.

RESULTS

Significantly more patients met the goal of A1C <7% in the CBEP compared to national estimates (CBEP: 47.1% vs. NHANES 1999-2000: 37%, p=0.003). Similar patterns were observed for BP (CBEP: 53.2% vs. NHANES 1999-2000: 35.8%, p<0.0001), TC (CBEP: 82% vs. NHANES 1999-2000: 48.2%, p<0.0001), and all three ABCs (CBEP: 22%, vs. NHANES 1999-2000: 7.3%, p<0.0001). The proportion of patients meeting all three ABC goals in the CBEP increased significantly over time (p<0.0001). Multivariate models demonstrated that patients not needing insulin (p<0.0001), and taking fewer BP (p<0.0001), and cholesterol-lowering medications (p<0.02) were significantly more likely to have ABCs in control.

CONCLUSIONS

Attainment of ABC goals is feasible in a CBEP and can be achieved at rates higher than national averages. Attention to factors that affect these goals is warranted.

摘要

目的

确定社区内分泌实践(CBEP)中糖化血红蛋白(A1C)、血压(BP)和总胆固醇(TC)(糖尿病ABC指标)的控制情况,并将其水平与全国平均水平进行比较。此外,确定与ABC指标控制相关的患者因素。

方法

对2000年至2004年期间因糖尿病管理而连续就诊的395例患者进行回顾性病历审查,以检查ABC指标的控制水平。使用多变量模型确定与控制相关的患者因素。

结果

与全国估计值相比,CBEP中达到A1C<7%目标的患者显著更多(CBEP:47.1% vs. 1999 - 2000年美国国家健康与营养检查调查(NHANES):37%,p = 0.003)。血压(CBEP:53.2% vs. 1999 - 2000年NHANES:35.8%,p<0.0001)、总胆固醇(CBEP:82% vs. 1999 - 2000年NHANES:48.2%,p<0.0001)以及所有三项ABC指标(CBEP:22%,vs. 1999 - 2000年NHANES:7.3%,p<0.0001)也观察到类似模式。CBEP中达到所有三项ABC目标的患者比例随时间显著增加(p<0.0001)。多变量模型表明,不需要胰岛素的患者(p<0.0001)、服用较少降压药(p<0.0001)和降脂药(p<0.02)的患者更有可能使ABC指标得到控制。

结论

在CBEP中实现ABC目标是可行的,且达成率高于全国平均水平。有必要关注影响这些目标的因素。

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