Fick Donna M, Mion Lorraine C, Beers Mark H, L Waller Jennifer
School of Nursing, 307C Health & Human Development East, The Pennsylvania State University, University Park, PA 16802, USA.
Res Nurs Health. 2008 Feb;31(1):42-51. doi: 10.1002/nur.20232.
The purpose of this study was to examine the prevalence of potentially inappropriate medication use (PIMs) among community-dwelling older adults and the association between PIMs and health care outcomes. Participants were 17,971 individuals age 65 years and older. PIM use was defined by the Beers criteria. Drug-related problems (DRPs) were defined using ICD-9 codes. Forty percent of the 17,971 individuals filled at least 1 PIM prescription, and 13% filled 2 or more PIM prescriptions. Overall DRP prevalence among those with at least 1 PIM prescription was 14.3% compared to 4.7% in the non-PIM group (p < .001). In conclusion, preventing PIM use may be important for decreasing medication-related problems, which are increasingly being recognized as requiring an integrated interdisciplinary approach.
本研究的目的是调查社区居住的老年人中潜在不适当用药(PIMs)的患病率以及PIMs与医疗保健结果之间的关联。参与者为17971名65岁及以上的个体。PIM的使用由Beers标准定义。药物相关问题(DRPs)使用ICD-9编码定义。在17971名个体中,40%的人至少开具了1张PIM处方,13%的人开具了2张或更多PIM处方。至少有1张PIM处方者的总体DRP患病率为14.3%,而非PIM组为4.7%(p < .001)。总之,预防PIM的使用对于减少药物相关问题可能很重要,而这些问题越来越被认为需要综合的跨学科方法。