Ritter J, Oehme J
Klin Wochenschr. 1976 Jul 1;54(13):647-8. doi: 10.1007/BF01469032.
Using a direct immunofluorescence technique and a spontaneous rosette formation with sheep red blood cells it could be demonstrated that the large mononuclear cells in infectious mononucleosis consisted mainly of T-lymphocytes. It is likely that infectious mononucleosis represents a primary B-lymphcoyte infection with the Epstein-Barr virus like in the Burkitt lymphoma. In contrast to this malignant lymphoma, interaction in infectious mononucleosis leads to a secondary T-lymphocyte proliferation.
采用直接免疫荧光技术以及与绵羊红细胞的自发玫瑰花结形成试验,可以证明传染性单核细胞增多症中的大单核细胞主要由T淋巴细胞组成。传染性单核细胞增多症可能像伯基特淋巴瘤一样,是由爱泼斯坦-巴尔病毒引起的原发性B淋巴细胞感染。与这种恶性淋巴瘤不同,传染性单核细胞增多症中的相互作用会导致继发性T淋巴细胞增殖。