Campbell O B, George A O, Shokunbi W A, Akang E E, Aghadiuno P U
Department of Radiology, University College Hospital (UCH), Ibadan, Nigeria.
Trop Geogr Med. 1991 Jul;43(3):317-22.
The management of Nigerian patients with cutaneous T-cell lymphoma (CTCL) is beset with various problems which are presented in this study. These problems include dearth of specialists medical personnel, shortage of radiotherapy facilities, high cost of chemotherapy drugs which an average patient cannot afford to buy. Cases of eight patients seen and managed over a 21 years period (1968-1989) were analysed. However, many CTCL cases might have been missed since we have acute shortage of medical specialists to carry out accurate diagnosis of this disease in Nigeria. The patients reviewed, received radiotherapy, and cytotoxic chemotherapy. Radiotherapy was found to be the optimum treatment for patients with stages I and II CTCL, who in this study had recurrence free periods of 30 to 60 months post radiotherapy. The authors recommend systemic cytotoxic chemotherapy and local radiotherapy for patients with late stages of CTCL as mainstay of treatment.
本研究介绍了尼日利亚皮肤T细胞淋巴瘤(CTCL)患者管理中存在的各种问题。这些问题包括专科医务人员匮乏、放疗设施短缺、化疗药物成本高昂,普通患者无力购买。分析了在21年期间(1968 - 1989年)诊治的8例患者病例。然而,由于尼日利亚严重缺乏医学专家对该病进行准确诊断,许多CTCL病例可能被漏诊。所回顾的患者接受了放疗和细胞毒性化疗。放疗被发现是I期和II期CTCL患者的最佳治疗方法,在本研究中,这些患者放疗后无复发期为30至60个月。作者建议,对于晚期CTCL患者,应以全身细胞毒性化疗和局部放疗作为主要治疗手段。