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[单纯性甲状腺肿非根治性甲状腺切除术中甲状腺下动脉结扎对机体钙磷代谢选定参数的影响评估]

[Evaluation of the effect of ligation of the inferior thyroid arteries during non-radical thyroidectomy in simple goiter on selected parameters of calcium-phosphate metabolism in the body].

作者信息

Kosiński B

机构信息

Oddziału Chirurgicznego Wojewódzkiego Szpitala Zespolonego w Szczecinie.

出版信息

Ann Acad Med Stetin. 1991;37:179-90.

PMID:1816751
Abstract

The aim of the paper was to evaluate the effect of inferior thyroid arteries ligation during the incomplete excision of the thyroid gland in patients with simple goitre, exerted on selected parameters of phosphate-calcium balance in the organism as compared with a group of patients, in whom no inferior thyroid arteries were ligated. The study material comprised 84 patients with simple goitre, free of other diseases. The evaluation covered the following parameters of the phosphate-calcium balance in the organism, namely: the concentration of total calcium, protein, dialyzing calcium, inorganic phosphate as well as immunoreactive parathyroid hormone. The study was performed three times: prior to operative procedure, directly after the operative procedure, and three months after the procedure. It has been shown that there are slight, but statistically significant, differences in the behaviour involving the concentration of total and dialyzing calcium as well as IRPTH in serum, depending on the applied operative technique. Directly after the procedure the changes affecting the studied parameters were more pronounced in patients with ligated inferior thyroid arteries. Three months after the operative procedure the mean concentration of IRPTH, total and dialyzing calcium was somewhat higher in patients, whose inferior thyroid arteries were ligated, than in patients, in whom the arteries were not ligated. The described changes were of subclinical character.

摘要

本文的目的是评估单纯性甲状腺肿患者在甲状腺不完全切除术中结扎甲状腺下动脉,与未结扎甲状腺下动脉的患者组相比,对机体磷钙平衡的选定参数所产生的影响。研究材料包括84例无其他疾病的单纯性甲状腺肿患者。评估涵盖了机体磷钙平衡的以下参数,即:总钙、蛋白质、可透析钙、无机磷以及免疫反应性甲状旁腺激素的浓度。研究在三个时间点进行:手术前、手术后即刻以及术后三个月。结果表明,根据所采用的手术技术,血清中总钙和可透析钙的浓度以及免疫反应性甲状旁腺激素在变化趋势上存在轻微但具有统计学意义的差异。术后即刻,甲状腺下动脉结扎患者中影响研究参数的变化更为明显。术后三个月,甲状腺下动脉结扎患者的免疫反应性甲状旁腺激素、总钙和可透析钙的平均浓度略高于未结扎动脉的患者。所述变化具有亚临床特征。

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